Institution
Hanyang University
Education•Seoul, South Korea•
About: Hanyang University is a education organization based out in Seoul, South Korea. It is known for research contribution in the topics: Thin film & Population. The organization has 29387 authors who have published 58815 publications receiving 1190144 citations. The organization is also known as: Hanyang Taehakkyo.
Topics: Thin film, Population, Oxide, Membrane, Catalysis
Papers published on a yearly basis
Papers
More filters
••
TL;DR: With continued improvement in technology and increasing clinical experience, one or more of these minimally invasive techniques may soon challenge surgical resection as the treatment of choice for patients with limited hepatic tumor.
Abstract: Six existing minimally invasive techniques for the treatment of primary and secondary malignant hepatic tumors—radio-frequency ablation, microwave ablation, laser ablation, cryoablation, ethanol ablation, and chemoembolization—are reviewed and debated by noted authorities from six institutions from around the world. All of the authors currently believe that surgery remains the treatment of choice for patients with resectable hepatic tumors. However, the clinical results of each of the minimally invasive techniques presented have exceeded those obtained with conventional chemotherapy or radiation therapy. Thus, for nonsurgical patients, these techniques are becoming standard independent or adjuvant therapies. In addition, with continued improvement in technology and increasing clinical experience, one or more of these minimally invasive techniques may soon challenge surgical resection as the treatment of choice for patients with limited hepatic tumor.
606 citations
••
TL;DR: The research utilized a double-bound dichotomous choice, and analysis by the nonparametric Turnbull method to suggest new classification of cost-effectiveness plane and methodology for decision making.
Abstract: Although the threshold of cost effectiveness of medical interventions is thought to be 20 000- 30 000 UK pounds in the UK, and $50 000-$100 000 in the US, it is well known that these values are unjustified, due to lack of explicit scientific evidence. We measured willingness-to-pay (WTP) for one additional quality-adjusted life-year gained to determine the threshold of the incremental cost-effectiveness ratio. Our study used the Internet to compare WTP for the additional year of survival in a perfect status of health in Japan, the Republic of Korea (ROK), Taiwan, Australia, the UK, and the US. The research utilized a double-bound dichotomous choice, and analysis by the nonparametric Turnbull method. WTP values were JPY 5 million (Japan), KWN 68 million (ROK), NT$ 2.1 million (Taiwan), 23 000 UK pounds (UK), AU$ 64 000 (Australia), and US$ 62 000 (US). The discount rates of outcome were estimated at 6.8% (Japan), 3.7% (ROK), 1.6% (Taiwan), 2.8% (UK), 1.9% (Australia), and 3.2% (US). Based on the current study, we suggest new classification of cost-effectiveness plane and methodology for decision making.
605 citations
••
Ocean University of China1, Commonwealth Scientific and Industrial Research Organisation2, University of New South Wales3, Hanyang University4, Yonsei University5, Georgia Institute of Technology6, University of Exeter7, University of Paris8, University of Reading9, Pohang University of Science and Technology10, National Oceanic and Atmospheric Administration11, Geophysical Fluid Dynamics Laboratory12, University of Tokyo13
TL;DR: A review of the state of knowledge on the El Nino/Southern Oscillation (ENSO), a natural climate phenomenon, can be found in this article, where the authors discuss recent advances and insights into how climate change will affect this natural climate varibility cycle.
Abstract: This Review looks at the state of knowledge on the El Nino/Southern Oscillation (ENSO), a natural climate phenomenon. It discusses recent advances and insights into how climate change will affect this natural climate varibility cycle. The El Nino/Southern Oscillation (ENSO) is the dominant climate phenomenon affecting extreme weather conditions worldwide. Its response to greenhouse warming has challenged scientists for decades, despite model agreement on projected changes in mean state. Recent studies have provided new insights into the elusive links between changes in ENSO and in the mean state of the Pacific climate. The projected slow-down in Walker circulation is expected to weaken equatorial Pacific Ocean currents, boosting the occurrences of eastward-propagating warm surface anomalies that characterize observed extreme El Nino events. Accelerated equatorial Pacific warming, particularly in the east, is expected to induce extreme rainfall in the eastern equatorial Pacific and extreme equatorward swings of the Pacific convergence zones, both of which are features of extreme El Nino. The frequency of extreme La Nina is also expected to increase in response to more extreme El Ninos, an accelerated maritime continent warming and surface-intensified ocean warming. ENSO-related catastrophic weather events are thus likely to occur more frequently with unabated greenhouse-gas emissions. But model biases and recent observed strengthening of the Walker circulation highlight the need for further testing as new models, observations and insights become available.
604 citations
••
TL;DR: The progress in chemical probes described here suggests that fluorescence imaging is a vital and rapidly developing field for interventional surgical imaging, as well as tumor diagnosis and therapy.
Abstract: Surgical resection of solid tumors is currently the gold standard and preferred therapeutic strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting the rapid growth of tumor cells and these two approaches are often combined to enhance treatment efficacy. However, surgery and chemotherapy inevitably lead to severe side effects and high systemic toxicity, which in turn results in poor prognosis. Precision medicine has promoted the development of treatment modalities that are developed to specifically target and kill tumor cells. Advances in in vivo medical imaging for visualizing tumor lesions can aid diagnosis, facilitate surgical resection, investigate therapeutic efficacy, and improve prognosis. In particular, the modality of fluorescence imaging has high specificity and sensitivity and has been utilized for medical imaging. Therefore, there are great opportunities for chemists and physicians to conceive, synthesize, and exploit new chemical probes that can image tumors and release chemotherapy drugs in vivo. This review focuses on small molecular ligand-targeted fluorescent imaging probes and fluorescent theranostics, including their design strategies and applications in clinical tumor treatment. The progress in chemical probes described here suggests that fluorescence imaging is a vital and rapidly developing field for interventional surgical imaging, as well as tumor diagnosis and therapy.
600 citations
••
Pusan National University1, University of Hawaii at Manoa2, Yonsei University3, Pohang University of Science and Technology4, Commonwealth Scientific and Industrial Research Organisation5, Hobart Corporation6, Ocean University of China7, University of Colorado Boulder8, Earth System Research Laboratory9, Georgia Institute of Technology10, University of Paris11, Pacific Marine Environmental Laboratory12, University of Washington13, University Corporation for Atmospheric Research14, Geophysical Fluid Dynamics Laboratory15, Leibniz Institute of Marine Sciences16, National Taiwan University17, Utah State University18, Monash University, Clayton campus19, University of Mary Washington20, University of Reading21, Centre national de la recherche scientifique22, Chonnam National University23, Met Office24, Ulsan National Institute of Science and Technology25, Asia-Pacific Economic Cooperation26, Bureau of Meteorology27, China Meteorological Administration28, University of New South Wales29, University of Exeter30, Chinese Academy of Sciences31, Hanyang University32, Gwangju Institute of Science and Technology33
TL;DR: A synopsis of the current understanding of the spatio-temporal complexity of this important climate mode and its influence on the Earth system is provided and a unifying framework that identifies the key factors for this complexity is proposed.
Abstract: El Nino events are characterized by surface warming of the tropical Pacific Ocean and weakening of equatorial trade winds that occur every few years Such conditions are accompanied by changes in atmospheric and oceanic circulation, affecting global climate, marine and terrestrial ecosystems, fisheries and human activities The alternation of warm El Nino and cold La Nina conditions, referred to as the El Nino–Southern Oscillation (ENSO), represents the strongest year-to-year fluctuation of the global climate system Here we provide a synopsis of our current understanding of the spatio-temporal complexity of this important climate mode and its influence on the Earth system
598 citations
Authors
Showing all 29583 results
Name | H-index | Papers | Citations |
---|---|---|---|
John A. Rogers | 177 | 1341 | 127390 |
Charles M. Lieber | 165 | 521 | 132811 |
Jongmin Lee | 150 | 2257 | 134772 |
Rajesh Kumar | 149 | 4439 | 140830 |
Prashant V. Kamat | 140 | 725 | 79259 |
Tae Jeong Kim | 132 | 1420 | 93959 |
Jie Liu | 131 | 1531 | 68891 |
Junghwan Goh | 128 | 1068 | 77137 |
Young Hee Lee | 122 | 1168 | 61107 |
Allan H. MacDonald | 119 | 926 | 56221 |
Terence G. Langdon | 117 | 1158 | 61603 |
Yang-Kook Sun | 117 | 781 | 58912 |
Sang Yup Lee | 117 | 1005 | 53257 |
Yoshinobu Unno | 115 | 875 | 66107 |
Xi Chen | 105 | 1547 | 52533 |