Institution
Islamic Azad University
Education•Tehran, Iran•
About: Islamic Azad University is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Population & Catalysis. The organization has 83635 authors who have published 113437 publications receiving 1275049 citations. The organization is also known as: Azad University.
Topics: Population, Catalysis, Adsorption, Fuzzy logic, Nonlinear system
Papers published on a yearly basis
Papers
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TL;DR: It is concluded that QR has significant beneficial effects on the sperm viability, motility, and serum total testosterone and could be effective for maintaining healthy sperm parameters and male reproductive function in diabetic rats.
Abstract: Quercetin (QR) is a strong antioxidant and has been shown to reduce oxidative stress in the long-term treatment of streptozotocin (STZ)-induced diabetes in animal models. Antioxidants have significant effects on spermatogenesis, sperm biology and oxidative stress, and changes in antioxidant capacity are considered to be involved in the pathogenesis of chronic diabetes mellitus. The present study aims to examine the influence of QR on spermatogenesis in STZ-induced diabetes in male Wistar rats. Animals (n = 50) were allocated into five groups: Group 1: Control rats given 0.5 ml of 20% glycerol in 0.9% normal saline. Group 2: Control rats given buffer (pH4.0).Group 3: diabetic controls. Group 4: rats given QR 15 mg/kg/day (i.p.). Group 5: STZ + QR rats. Animals were kept in standard conditions. At the end of the experiment (28th day), blood samples were taken for determination of testosterone, total antioxidant capacity, and levels of malondialdehyde and oxidized low-density lipoprotein. All rats were euthanized, testes were dissected out and spermatozoa were collected from the epididymis for analysis. Sperm numbers, percentages of sperm viability and motility, and total serum testosterone increased significantly in QR-treated diabetic rats (P < 0.05) compared with control groups. In histopathology, degeneration and inflammation in testes cells associated with diabetes were improved and testes weights in the QR-treated diabetic group decreased significantly in comparison with controls (P < 0.05). We conclude that QR has significant beneficial effects on the sperm viability, motility, and serum total testosterone and could be effective for maintaining healthy sperm parameters and male reproductive function in diabetic rats.
176 citations
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TL;DR: Reinforcement learning with a Q-factor algorithm is used to enhance performance of the scheduling method proposed for dynamic job shop scheduling (DJSS) problem which considers random job arrivals and machine breakdowns.
176 citations
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Vardan Khachatryan, Albert M. Sirunyan, Armen Tumasyan, Wolfgang Adam1 +2205 more•Institutions (182)
TL;DR: In this paper, a model-independent search for a narrow resonance produced in proton-proton collisions at square root(s) = 8 TeV and decaying to a pair of 125 GeV Higgs bosons that in turn each decays into bottom quark-antiquark pairs is performed by the CMS experiment at the LHC.
176 citations
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TL;DR: In this article, the energy procurement problem for a large electricity consumer is solved under various resources and the results of information gap decision theory are presented in three different strategies for the large consumer.
176 citations
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TL;DR: The role of HsfA and HsfC2 in regulation of Hsp genes in wheat is demonstrated, suggesting an important regulatory role during heat stress.
Abstract: Heat shock factors (Hsfs) play a central regulatory role in acquired thermotolerance. To understand the role of the major molecular players in wheat adaptation to heat stress, the Hsf family was investigated in Triticum aestivum. Bioinformatic and phylogenetic analyses identified 56 TaHsf members, which are classified into A, B, and C classes. Many TaHsfs were constitutively expressed. Subclass A6 members were predominantly expressed in the endosperm under non-stress conditions. Upon heat stress, the transcript levels of A2 and A6 members became the dominant Hsfs, suggesting an important regulatory role during heat stress. Many TaHsfA members as well as B1, C1, and C2 members were also up-regulated during drought and salt stresses. The heat-induced expression profiles of many heat shock protein (Hsp) genes were paralleled by those of A2 and A6 members. Transactivation analysis revealed that in addition to TaHsfA members (A2b and A4e), overexpression of TaHsfC2a activated expression of TaHsp promoter-driven reporter genes under non-stress conditions, while TaHsfB1b and TaHsfC1b did not. Functional heat shock elements (HSEs) interacting with TaHsfA2b were identified in four TaHsp promoters. Promoter mutagenesis analysis demonstrated that an atypical HSE (GAACATTTTGGAA) in the TaHsp17 promoter is functional for heat-inducible expression and transactivation by Hsf proteins. The transactivation of Hsp promoter-driven reporter genes by TaHsfC2a also relied on the presence of HSE. An activation motif in the C-terminal domain of TaHsfC2a was identified by amino residue substitution analysis. These data demonstrate the role of HsfA and HsfC2 in regulation of Hsp genes in wheat.
176 citations
Authors
Showing all 83704 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ajit Kumar Mohanty | 141 | 1124 | 93062 |
Pierluigi Paolucci | 138 | 1965 | 105050 |
Eric Conte | 132 | 1206 | 84593 |
Patrizia Azzi | 132 | 1275 | 83686 |
D. Del Re | 131 | 1406 | 87230 |
Jean-Laurent Agram | 128 | 1221 | 84423 |
Seyed Mohsen Etesami | 128 | 1101 | 76488 |
Jean-Charles Fontaine | 128 | 1190 | 84011 |
Roberta Arcidiacono | 128 | 1322 | 80917 |
Tejinder Virdee | 128 | 1208 | 74372 |
Frank Hartmann | 127 | 1116 | 81455 |
Paolo Azzurri | 126 | 1058 | 81651 |
Achim Stahl | 124 | 1248 | 111121 |
Federica Primavera | 120 | 876 | 63895 |
Riccardo Andrea Manzoni | 120 | 946 | 67897 |