Institution
Jilin University
Education•Changchun, China•
About: Jilin University is a education organization based out in Changchun, China. It is known for research contribution in the topics: Catalysis & Apoptosis. The organization has 101453 authors who have published 88966 publications receiving 1444456 citations. The organization is also known as: Jílín Dàxué.
Topics: Catalysis, Apoptosis, Cancer, Adsorption, Cell growth
Papers published on a yearly basis
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334 citations
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Capital Medical University1, Shandong University2, Wuhan University3, Jilin University4, Chongqing Medical University5, Sun Yat-sen University6, Zhejiang University7, Third Military Medical University8, Xi'an Jiaotong University9, Fudan University10, Qingdao University11, Central South University12, China-Japan Friendship Hospital13, Henry Ford Hospital14, McGill University15
TL;DR: The socioeconomic costs of Alzheimer's disease in China and its impact on global economic burden remain uncertain.
Abstract: Introduction The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain. Methods We collected data from 3098 patients with AD in 81 representative centers across China and estimated AD costs for individual patient and total patients in China in 2015. Based on this data, we re-estimated the worldwide costs of AD. Results The annual socioeconomic cost per patient was US $19,144.36, and total costs were US $167.74 billion in 2015. The annual total costs are predicted to reach US $507.49 billion in 2030 and US $1.89 trillion in 2050. Based on our results, the global estimates of costs for dementia were US $957.56 billion in 2015, and will be US $2.54 trillion in 2030, and US $9.12 trillion in 2050, much more than the predictions by the World Alzheimer Report 2015. Discussion China bears a heavy burden of AD costs, which greatly change the estimates of AD cost worldwide.
334 citations
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331 citations
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Radboud University Nijmegen1, University of Toronto2, Complutense University of Madrid3, Aix-Marseille University4, Carnegie Mellon University5, King's College London6, New York University7, Ben-Gurion University of the Negev8, Goethe University Frankfurt9, Oregon Health & Science University10, University of Pittsburgh11, South London and Maudsley NHS Foundation Trust12, University of São Paulo13, University of Southern California14, George Washington University15, Jilin University16, Trinity College, Dublin17
TL;DR: Findings suggest an interplay in the abnormal development of the striatal, frontal, and temporal regions in ASD across the lifespan, using a well-established, validated, publicly available analysis pipeline.
Abstract: Objective:Neuroimaging studies show structural differences in both cortical and subcortical brain regions in children and adults with autism spectrum disorder (ASD) compared with healthy subjects. Findings are inconsistent, however, and it is unclear how differences develop across the lifespan. The authors investigated brain morphometry differences between individuals with ASD and healthy subjects, cross-sectionally across the lifespan, in a large multinational sample from the Enhancing Neuroimaging Genetics Through Meta-Analysis (ENIGMA) ASD working group.Method:The sample comprised 1,571 patients with ASD and 1,651 healthy control subjects (age range, 2–64 years) from 49 participating sites. MRI scans were preprocessed at individual sites with a harmonized protocol based on a validated automated-segmentation software program. Mega-analyses were used to test for case-control differences in subcortical volumes, cortical thickness, and surface area. Development of brain morphometry over the lifespan was mo...
331 citations
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TL;DR: A green, facile hydrothermal synthesis of highly efficient red emissive nitrogen-doped carbonized polymer dots (CPDs) with optimal emission at around 630 nm are reported, demonstrating that most CPDs and their metabolites are not only excreted in urine but also excrete by hepatobiliary system in a rapid manner.
Abstract: Carbon dots with long-wavelength emissions, high quantum yield (QY) and good biocompatibility are highly desirable for biomedical applications. Herein, a green, facile hydrothermal synthesis of highly efficient red emissive nitrogen-doped carbonized polymer dots (CPDs) with optimal emission at around 630 nm are reported. The red emissive CPDs possess a variety of superior properties including excellent water dispersibility, good biocompatibility, narrow bandwidth emission, an excitation-independent emission, and high QY (10.83% (in water) and 31.54% (in ethanol)). Further studies prove that such strong red fluorescence is ascribed to the efficient conjugated aromatic π systems and hydrogen bonds of CPDs. And the fluorescence properties of CPDs can be regulated by adjusting the dosage of HNO3 before the reaction. Additionally, the as-prepared CPDs are successfully used as a fluorescent probe for bioimaging, both in vitro and in vivo. More importantly, biodistribution results demonstrate that most CPDs and their metabolites are not only excreted in urine but also excreted by hepatobiliary system in a rapid manner. Besides, the CPDs could easily cross the blood brain barrier, which may provide a valuable strategy for the theranostics of some brain diseases through real-time tracking.
331 citations
Authors
Showing all 101943 results
Name | H-index | Papers | Citations |
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Yang Yang | 171 | 2644 | 153049 |
Yury Gogotsi | 171 | 956 | 144520 |
Lei Jiang | 170 | 2244 | 135205 |
Gang Chen | 167 | 3372 | 149819 |
Dongyuan Zhao | 160 | 872 | 106451 |
Rui Zhang | 151 | 2625 | 107917 |
Xiaodong Wang | 135 | 1573 | 117552 |
Avelino Corma | 134 | 1049 | 89095 |
Jie Liu | 131 | 1531 | 68891 |
Shuai Liu | 129 | 1095 | 80823 |
Yang Liu | 129 | 2506 | 122380 |
Sheng Dai | 122 | 985 | 63472 |
Xin Wang | 121 | 1503 | 64930 |
Simon A. Wilde | 118 | 390 | 45547 |
Shaojun Dong | 118 | 873 | 57337 |