Sapienza University of Rome

About: Sapienza University of Rome is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Population & Medicine. The organization has 62002 authors who have published 155468 publications receiving 4397244 citations. The organization is also known as: La Sapienza & Università La Sapienza di Roma.

Observation of the Doubly Charmed Baryon Ξcc

Abstract: A highly significant structure is observed in the Λc+K-π+π+ mass spectrum, where the Λc+ baryon is reconstructed in the decay mode pK-π+. The structure is consistent with originating from a weakly decaying particle, identified as the doubly charmed baryon Ξcc++. The difference between the masses of the Ξcc++ and Λc+ states is measured to be 1334.94±0.72(stat.)±0.27(syst.) MeV/c2, and the Ξcc++ mass is then determined to be 3621.40±0.72(stat.)±0.27(syst.)±0.14(Λc+) MeV/c2, where the last uncertainty is due to the limited knowledge of the Λc+ mass. The state is observed in a sample of proton-proton collision data collected by the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.7 fb-1, and confirmed in an additional sample of data collected at 8 TeV.

The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

Abstract: In this paper we report on the cloning and characterization of mouse CCR8. Like its human homologue, it is predominantly expressed in the thymus. In the periphery, murine CCR8 mRNA was found most abundantly expressed in activated Th2-polarized cells and in NK1.1+ CD4+ T cells. Human CCR8 is also preferentially expressed in human Th2-polarized cells and clones. This pattern of expression suggests that CCR8 is part of a Th2-specific gene expression program. The CCR8 ligands I-309 and its mouse homologue T cell activation gene 3 (TCA-3) are potent chemoattractants for Th2-polarized cells. Taken together, these observations strongly suggest that CCR8 plays a role in the control of Th2 responses, and may represent a potential target for treatment of allergic diseases.

Spin-glass theory for pedestrians

Abstract: In these notes the main theoretical concepts and techniques in the field of mean-field spin glasses are reviewed in a compact and pedagogical way, for the benefit of the graduate and undergraduate student. One particular spin-glass model is analysed (the p-spin spherical model) by using three different approaches: thermodynamics, covering pure states, overlaps, overlap distribution, replica symmetry breaking, and the static transition; dynamics, covering the generating functional method, generalized Langevin equation, equations for the correlation and the response, the mode coupling approximation, and the dynamical transition; and finally complexity, covering the mean-field (Thouless–Anderson–Palmer) free energy, metastable states, entropy crisis, threshold energy, and saddles. Particular attention has been paid to the mutual consistency of the results obtained from the different methods.

Final model independent result of DAMA/LIBRA–phase1

Abstract: The results obtained with the total exposure of 1.04 ton x yr collected by DAMA/LIBRA-phase1 deep underground at the Gran Sasso National Laboratory (LNGS) of the I.N.F.N. during 7 annual cycles (i.e. adding a further 0.17 ton x yr exposure) are presented. The DAMA/LIBRA-phase1 data give evidence for the presence of Dark Matter (DM) particles in the galactic halo, on the basis of the exploited model independent DM annual modulation signature by using highly radio-pure NaI(Tl) target, at 7.5 sigma C. L. Including also the first generation DAMA/NaI experiment (cumulative exposure 1.33 ton x yr, corresponding to 14 annual cycles), the C. L. is 9.3 sigma and the modulation amplitude of the single-hit events in the (2-6) keV energy interval is: (0.0112 +/- 0.0012) cpd/kg/keV; the measured phase is (144 +/- 7) days and the measured period is (0.998 +/- 0.002) yr, values well in agreement with those expected for DM particles. No systematic or side reaction able to mimic the exploited DM signature has been found or suggested by anyone over more than a decade.