Institution
University of Akron
Education•Akron, Ohio, United States•
About: University of Akron is a education organization based out in Akron, Ohio, United States. It is known for research contribution in the topics: Polymer & Polymerization. The organization has 17401 authors who have published 29127 publications receiving 702386 citations. The organization is also known as: The University of Akron.
Topics: Polymer, Polymerization, Natural rubber, Copolymer, Monomer
Papers published on a yearly basis
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TL;DR: This article revisited the issue of socioeconomic and spatial disparities that have characterized Ghana since colonial times, emphasizing the period from 1983 when Ghana's Structural Adjustment Programs (SAPs) began, and examined current patterns of socioeconomic disparities with emphasis on the distribution of, and access to, health, education, basic services, and the like.
Abstract: Since 1983, Ghana has been undergoing World Bank and International Monetary Fund (IMF) sponsored Structural Adjustment Programs (SAPs). The implementation of the SAPs, it is claimed, has arrested Ghana's economy from complete collapse, resulted in consistent growth in GDP averaging 6% over the past decade, reduced inflation levels, created budget surplus, and increased export earnings. Compared to the 1970s, these are the best of times indeed. But while these SAPs-derived improvements in the national economy have been recorded at the macro level, the benefits at the micro level are a matter of considerable debate. This study revisits the issue of socioeconomic and spatial disparities that have characterized Ghana since colonial times, emphasizing the period from 1983 when Ghana's SAPs began. It examines current patterns of socioeconomic disparities with emphasis on the distribution of, and access to, health, education, basic services, and the like. The study focuses on urban-rural as well as interregional...
301 citations
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PSL Research University1, University of Michigan2, University of Akron3, University of Strasbourg4, Boston University5, National Autonomous University of Mexico6, University of California, Santa Barbara7, Pennsylvania State University8, University of Naples Federico II9, Imperial College London10, Leidos11, Shanghai Jiao Tong University12, Ton Duc Thang University13, University of Bordeaux14, University of Manchester15, Western Washington University16, Polish Academy of Sciences17, North Carolina State University18, Ben-Gurion University of the Negev19, Forschungszentrum Jülich20, University of Texas Medical Branch21, University of Minnesota22, Fudan University23, University of Paris24
TL;DR: In this paper, the authors review what computer, in vitro, in vivo, and pharmacological experiments tell us about the accumulation and deposition of the oligomers of the (Aβ, tau), α-synuclein, IAPP, and superoxide dismutase 1 proteins, which have been the mainstream concept underlying Alzheimer's disease, Parkinson's disease (PD), type II diabetes (T2D), and amyotrophic lateral sclerosis (ALS) research.
Abstract: Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting either the central nervous system or a variety of peripheral tissues. Structural and dynamic characterization of all species along the pathways from monomers to fibrils is challenging by experimental and computational means because they involve intrinsically disordered proteins in most diseases. Yet understanding how amyloid species become toxic is the challenge in developing a treatment for these diseases. Here we review what computer, in vitro, in vivo, and pharmacological experiments tell us about the accumulation and deposition of the oligomers of the (Aβ, tau), α-synuclein, IAPP, and superoxide dismutase 1 proteins, which have been the mainstream concept underlying Alzheimer's disease (AD), Parkinson's disease (PD), type II diabetes (T2D), and amyotrophic lateral sclerosis (ALS) research, respectively, for many years.
300 citations
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TL;DR: Flexible graphene polyimide nanocomposites with superior mechanical properties over those of neatpolyimide resin have been prepared by solution blending and exhibited excellent compatibility with N-methyl-2-pyrrolidone.
Abstract: Flexible graphene polyimide nanocomposites (0.1–4 wt %) with superior mechanical properties over those of neat polyimide resin have been prepared by solution blending. Imide moieties were grafted to amine-functionalized graphene using a step-by-step condensation and thermal imidization method. The imide-functionalized graphene exhibited excellent compatibility with N-methyl-2-pyrrolidone. The dynamic storage moduli of the graphene polyimide nanocomposites increased linearly with increasing graphene content for both unmodified graphene and imidized graphene. Moduli of the imidized graphene nanocomposites were 25–30% higher than those of unmodified graphene nanocomposites. Both neat polyimide and polyimide nanocomposites exhibited shape memory effects with a triggering temperature of 230 °C. where addition of graphene improved the recovery rate. Addition of graphene improved thermal stability of the polyimide nanocomposites for both graphene and modified graphene.
298 citations
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TL;DR: Findings indicated that online learner participation and patterns of participation are influenced by the following factors: technology and interface characteristics, content area experience, student roles and instructional tasks, and information overload.
Abstract: This study explored what factors influenced learner participation in two sections of a graduate online course at a Midwestern university. Findings indicated that online learner participation and patterns of participation are influenced by the following factors: technology and interface characteristics, content area experience, student roles and instructional tasks, and information overload. Effective online learning requires interdependence for a shared understanding of learning goals in a learning community. Monitoring student participation and patterns of participation closely can help instructors identify student needs and scaffold learning accordingly.
298 citations
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TL;DR: It is reported that Ang II and Ang-(1-7) differentially modulate rat aortic vascular smooth muscle cell growth and inhibition of proliferation appears to be mediated by a novel angiotensin receptor that is not inhibited by AT1 or AT2 receptor antagonists.
Abstract: Although angiotensin II (Ang II) and the heptapeptide Ang-(1-7) differ by only one amino acid, the two peptides produce different responses in vascular smooth muscle cells. We previously showed that Ang II stimulated phosphoinositide hydrolysis, whereas Ang II and Ang-(1-7) released prostaglandins. We now report that Ang II and Ang-(1-7) differentially modulate rat aortic vascular smooth muscle cell growth. Ang-(1-7) inhibited [3H]thymidine incorporation in response to stimulation by fetal bovine serum, platelet-derived growth factor, or Ang II. The reduction in serum-stimulated thymidine incorporation by Ang-(1-7) depended on the concentration of the heptapeptide over the range of 1 nmol/L to 1 mumol/L, with a maximal inhibition of 60% by 1 mumol/L Ang-(1-7). Ang-(1-7) also inhibited the serum-stimulated increase in cell number to a maximum of 77% by 1 mumol/L Ang-(1-7). The attenuation of serum-stimulated thymidine incorporation by Ang-(1-7) was unaffected by antagonists selective for angiotensin type 1 (AT1) or type 2 (AT2) receptors; however, [Sar1,Ile1]Ang II and [Sar1,Thr2]Ang II were effective antagonists, indicating that growth inhibition by Ang-(1-7) was a result of angiotensin receptor activation. In contrast, Ang II stimulated [3H]thymidine incorporation in cultured vascular smooth muscle cells over the same concentration range, with a maximal stimulation of 314% at 1 mumol/L Ang II. Ang II also increased the total number of cells (to 145% of control), suggesting that enhanced thymidine incorporation was associated with vascular smooth muscle cell proliferation. The AT1 antagonist losartan or L-158,809 but not AT2 antagonists blocked [3H]thymidine incorporation by Ang II. These results suggest that Ang-(1-7) and Ang II exhibit opposite effects on the regulation of vascular smooth muscle cell growth. The inhibition of proliferation by Ang-(1-7) appears to be mediated by a novel angiotensin receptor that is not inhibited by AT1 or AT2 receptor antagonists.
297 citations
Authors
Showing all 17460 results
Name | H-index | Papers | Citations |
---|---|---|---|
Pulickel M. Ajayan | 176 | 1223 | 136241 |
Alan J. Heeger | 171 | 913 | 147492 |
Josef M. Penninger | 154 | 700 | 107295 |
Liming Dai | 141 | 781 | 82937 |
Chao Zhang | 127 | 3119 | 84711 |
Ulrich S. Schubert | 122 | 2229 | 85604 |
Vijay P. Singh | 106 | 1699 | 55831 |
Andrea Natale | 106 | 945 | 52520 |
Bruce J. Avolio | 105 | 220 | 69603 |
Thomas A. Lipo | 103 | 682 | 43110 |
Virgil Percec | 101 | 798 | 42465 |
Chang Liu | 97 | 1099 | 39573 |
Gareth H. McKinley | 97 | 467 | 34624 |
Paul J. Flory | 93 | 247 | 59120 |
Soo-Jin Park | 86 | 1282 | 37204 |