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University of South Carolina

EducationColumbia, South Carolina, United States
About: University of South Carolina is a education organization based out in Columbia, South Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 25792 authors who have published 59995 publications receiving 2246122 citations. The organization is also known as: USC & U.S.C..


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Journal ArticleDOI
TL;DR: In this paper, a mathematical model for a complete lithium-sulfur cell is presented, which includes various electrochemical and chemical reactions, multicomponent transport phenomena in the electrolyte, and the charge transfer within and between solid and liquid phases.
Abstract: A mathematical model is presented for a complete lithium-sulfur cell. The model includes various electrochemical and chemical (precipitation) reactions, multicomponent transport phenomena in the electrolyte, and the charge transfer within and between solid and liquid phases. A change in the porosity of the porous cathode and separator due to precipitation reactions is also included in the model. The model is used to explain the physical reasons for the two-stage discharge profiles that are typically obtained for lithium-sulfur cells.

318 citations

Journal ArticleDOI
Abstract: Although normative questions about the role of the Supreme Court as a countermajoritarian institution have long excited controversy in democratic theory, empirical questions about how far the Court acts contrary to majoritarian opinion have received less attention. Time series analyses for the period 1956–89 indicate the existence of a reciprocal and positive relationship between long-term trends in aggregate public opinion and the Court's collective decisions. The Court's ideological composition changes in response to previous shifts in the partisan and ideological orientation of the president and Congress. The Court also responds to public opinion at the margins even in the absence of membership change. Since 1981, the relationship has vanished or turned negative in direction. The Court's ideological balance has been upset by an unbroken string of conservative-to-moderate appointments, thereby undermining the dynamics that promote judicial responsiveness and raising questions about the majoritarianism of the contemporary and future Court.

318 citations

Journal ArticleDOI
TL;DR: In this paper, the authors use a biocomplexity framework to provide a perspective of the consequences of climate change for coastal wetland ecogeomorphology, focusing on three dimensions of change: sea level rise, changes in storm frequency and intensity, and changes in freshwater, sediment, and nutrient inputs.
Abstract: Climate impacts on coastal and estuarine systems take many forms and are dependent on the local conditions, including those set by humans. We use a biocomplexity framework to provide a perspective of the consequences of climate change for coastal wetland ecogeomorphology. We concentrate on three dimensions of climate change affects on ecogeomorphology: sea level rise, changes in storm frequency and intensity, and changes in freshwater, sediment, and nutrient inputs. While sea level rise, storms, sedimentation, and changing freshwater input can directly impact coastal and estuarine wetlands, biological processes can modify these physical impacts. Geomorphological changes to coastal and estuarine ecosystems can induce complex outcomes for the biota that are not themselves intuitively obvious because they are mediated by networks of biological interactions. Human impacts on wetlands occur at all scales. At the global scale, humans are altering climate at rapid rates compared to the historical and recent geological record. Climate change can disrupt ecological systems if it occurs at characteristic time scales shorter than ecological system response and causes alterations in ecological function that foster changes in structure or alter functional interactions. Many coastal wetlands can adjust to predicted climate change, but human impacts, in combination with climate change, will significantly affect coastal wetland ecosystems. Management for climate change must strike a balance between that which allows pulsing of materials and energy to the ecosystems and promotes ecosystem goods and services, while protecting human structures and activities. Science-based management depends on a multi-scale understanding of these biocomplex wetland systems. Causation is often associated with multiple factors, considerable variability, feedbacks, and interferences. The impacts of climate change can be detected through monitoring and assessment of historical or geological records. Attribution can be inferred through these in conjunction with experimentation and modeling. A significant challenge to allow wise management of coastal wetlands is to develop observing systems that act at appropriate scales to detect global climate change and its effects in the context of the various local and smaller scale effects.

317 citations

Journal ArticleDOI
TL;DR: A double dissociation in ventral pallidum subregional roles in drug seeking is likely to be important for understanding the mesocorticolimbic circuits underlying reward seeking and addiction.
Abstract: The ventral pallidum is centrally positioned within mesocorticolimbic reward circuits, and its dense projection to the ventral tegmental area (VTA) regulates neuronal activity there. However, the ventral pallidum is a heterogeneous structure, and how this complexity affects its role within wider reward circuits is unclear. We found that projections to VTA from the rostral ventral pallidum (RVP), but not the caudal ventral pallidum (CVP), were robustly Fos activated during cue-induced reinstatement of cocaine seeking--a rat model of relapse in addiction. Moreover, designer receptor-mediated transient inactivation of RVP neurons, their terminals in VTA or functional connectivity between RVP and VTA dopamine neurons blocked the ability of drug-associated cues (but not a cocaine prime) to reinstate cocaine seeking. In contrast, CVP neuronal inhibition blocked cocaine-primed, but not cue-induced, reinstatement. This double dissociation in ventral pallidum subregional roles in drug seeking is likely to be important for understanding the mesocorticolimbic circuits underlying reward seeking and addiction.

317 citations


Authors

Showing all 26109 results

NameH-indexPapersCitations
Robert M. Califf1961561167961
Eric J. Topol1931373151025
Bernard Rosner1901162147661
Hyun-Chul Kim1764076183227
James F. Sallis169825144836
Steven N. Blair165879132929
Rodney S. Ruoff164666194902
David Cella1561258106402
Claude Bouchard1531076115307
Wei Zheng1511929120209
James M. Tour14385991364
Tim Adye1431898109010
John D. Scott13562583878
Anders Pape Møller135103471713
Lars Klareskog13169763281
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023110
2022503
20213,472
20203,344
20193,000
20182,668