Institution
University of South Carolina
Education•Columbia, South Carolina, United States•
About: University of South Carolina is a education organization based out in Columbia, South Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 25792 authors who have published 59995 publications receiving 2246122 citations. The organization is also known as: USC & U.S.C..
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TL;DR: In this paper, the photoresponse measured as a function of the gate voltage exhibited a maximum near the threshold voltage, which can be explained by the combined effect of exponential decrease of the electron density and the gate leakage current.
Abstract: We present an experimental and theoretical study of nonresonant detection of subterahertz radiation in GaAs/AlGaAs and GaN/AlGaN heterostructure field effect transistors. The experiments were performed in a wide range of temperatures (8–300 K) and for frequencies ranging from 100 to 600 GHz. The photoresponse measured as a function of the gate voltage exhibited a maximum near the threshold voltage. The results were interpreted using a theoretical model that shows that the maximum in photoresponse can be explained by the combined effect of exponential decrease of the electron density and the gate leakage current.
393 citations
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Pennsylvania State University1, Edinburgh Napier University2, Hogeschool van Amsterdam3, Netherlands Cancer Institute4, University of Amsterdam5, University of South Carolina6, Northern Arizona University7, Wingate University8, Harvard University9, Mayo Clinic10, Edith Cowan University11, American Cancer Society12, University of California, San Francisco13, George Mason University14, Kaiser Permanente15, Penn State Cancer Institute16, National Institutes of Health17, Macmillan Cancer Support18, New York University19, Oregon Health & Science University20, University of British Columbia21
TL;DR: There is a call to action for key stakeholders to create the infrastructure and cultural adaptations needed so that all people living with and beyond cancer can be as active as is possible for them.
Abstract: Multiple organizations around the world have issued evidence-based exercise guidance for patients with cancer and cancer survivors. Recently, the American College of Sports Medicine has updated its exercise guidance for cancer prevention as well as for the prevention and treatment of a variety of cancer health-related outcomes (eg, fatigue, anxiety, depression, function, and quality of life). Despite these guidelines, the majority of people living with and beyond cancer are not regularly physically active. Among the reasons for this is a lack of clarity on the part of those who work in oncology clinical settings of their role in assessing, advising, and referring patients to exercise. The authors propose using the American College of Sports Medicine's Exercise Is Medicine initiative to address this practice gap. The simple proposal is for clinicians to assess, advise, and refer patients to either home-based or community-based exercise or for further evaluation and intervention in outpatient rehabilitation. To do this will require care coordination with appropriate professionals as well as change in the behaviors of clinicians, patients, and those who deliver the rehabilitation and exercise programming. Behavior change is one of many challenges to enacting the proposed practice changes. Other implementation challenges include capacity for triage and referral, the need for a program registry, costs and compensation, and workforce development. In conclusion, there is a call to action for key stakeholders to create the infrastructure and cultural adaptations needed so that all people living with and beyond cancer can be as active as is possible for them.
392 citations
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TL;DR: Intervention studies which suggest that the restoration of insulin activity in the hippocampus may be an effective strategy to alleviate the cognitive decline associated with T2DM and AD are discussed.
Abstract: Clinical studies suggest a link between type 2 diabetes mellitus (T2DM) and insulin resistance (IR) and cognitive dysfunction, but there are significant gaps in our knowledge of the mechanisms underlying this relationship. Animal models of IR help to bridge these gaps and point to hippocampal IR as a potential mediator of cognitive dysfunction in T2DM, as well as in Alzheimer disease (AD). This Review highlights these observations and discusses intervention studies which suggest that the restoration of insulin activity in the hippocampus may be an effective strategy to alleviate the cognitive decline associated with T2DM and AD.
392 citations
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TL;DR: A comprehensive school-based intervention can increase regular participation in vigorous physical activity among high-school girls and help to reduce the prevalence of obesity among this group.
Abstract: Objectives. Many adolescent girls fail to meet national guidelines for physical activity, and the prevalence of obesity is increasing among this group. Our study examined the effects of a comprehensive school-based intervention on physical activity among high-school girls.Methods. A group-randomized controlled field trial was conducted at 24 high schools. A school-based sample of 2744 girls (48.7% African American, 46.7% White) participated in a measurement protocol when they were in eighth and then ninth grade. A comprehensive physical activity intervention was designed to change the instructional program and the school environment to increase support for physical activity among girls.Results. At follow-up, 45% of girls in the intervention schools and 36% of girls in the control schools reported vigorous physical activity during an average of 1 or more 30-minute time blocks per day over a 3-day period.Conclusions. A comprehensive school-based intervention can increase regular participation in vigorous ph...
392 citations
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TL;DR: A novel linear model for quantile regression (QR) that includes random effects in order to account for the dependence between serial observations on the same subject is proposed and appears to be a robust alternative to the mean regression with random effects when the location parameter of the conditional distribution of the response is of interest.
Abstract: In longitudinal studies, measurements of the same individuals are taken repeatedly through time. Often, the primary goal is to characterize the change in response over time and the factors that influence change. Factors can affect not only the location but also more generally the shape of the distribution of the response over time. To make inference about the shape of a population distribution, the widely popular mixed-effects regression, for example, would be inadequate, if the distribution is not approximately Gaussian. We propose a novel linear model for quantile regression (QR) that includes random effects in order to account for the dependence between serial observations on the same subject. The notion of QR is synonymous with robust analysis of the conditional distribution of the response variable. We present a likelihood-based approach to the estimation of the regression quantiles that uses the asymmetric Laplace density. In a simulation study, the proposed method had an advantage in terms of mean squared error of the QR estimator, when compared with the approach that considers penalized fixed effects. Following our strategy, a nearly optimal degree of shrinkage of the individual effects is automatically selected by the data and their likelihood. Also, our model appears to be a robust alternative to the mean regression with random effects when the location parameter of the conditional distribution of the response is of interest. We apply our model to a real data set which consists of self-reported amount of labor pain measurements taken on women repeatedly over time, whose distribution is characterized by skewness, and the significance of the parameters is evaluated by the likelihood ratio statistic.
392 citations
Authors
Showing all 26109 results
Name | H-index | Papers | Citations |
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Robert M. Califf | 196 | 1561 | 167961 |
Eric J. Topol | 193 | 1373 | 151025 |
Bernard Rosner | 190 | 1162 | 147661 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
James F. Sallis | 169 | 825 | 144836 |
Steven N. Blair | 165 | 879 | 132929 |
Rodney S. Ruoff | 164 | 666 | 194902 |
David Cella | 156 | 1258 | 106402 |
Claude Bouchard | 153 | 1076 | 115307 |
Wei Zheng | 151 | 1929 | 120209 |
James M. Tour | 143 | 859 | 91364 |
Tim Adye | 143 | 1898 | 109010 |
John D. Scott | 135 | 625 | 83878 |
Anders Pape Møller | 135 | 1034 | 71713 |
Lars Klareskog | 131 | 697 | 63281 |