2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Paul K. Whelton,Robert M. Carey,Wilbert S. Aronow,Donald E. Casey,Karen J. Collins,Cheryl Dennison Himmelfarb,Sondra M. DePalma,Samuel S. Gidding,Kenneth Jamerson,Daniel W. Jones,Eric J. MacLaughlin,Paul Muntner,Bruce Ovbiagele,Sidney C. Smith,Crystal C. Spencer,Randall S. Stafford,Sandra J. Taler,Randal J. Thomas,Kim A. Williams,Jeff D. Williamson,Jackson T. Wright +20 more
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Since 1980, the American College of Cardiology and American Heart Association have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health.Abstract:
Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisoryread more
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Facility-Level Variations in Kidney Disease Care among Veterans with Diabetes and CKD
Sankar D. Navaneethan,Julia M. Akeroyd,David J Ramsey,Sarah T. Ahmed,Shiva Raj Mishra,Laura A. Petersen,Paul Muntner,Christie M. Ballantyne,Christie M. Ballantyne,Wolfgang C. Winkelmayer,Venkat Ramanathan,Salim S. Virani +11 more
TL;DR: Among patients with diabetes and CKD, at facility-level, ordering of laboratory tests, and scheduling of nephrology referrals in eligible patients remains suboptimal, with substantial variations across facilities.
Journal ArticleDOI
Nocturnal Mean Oxygen Saturation Is Associated with Secondary Polycythemia in Young Adults with Obstructive Sleep Apnea, Especially in Men.
TL;DR: Nocturnal mean SpO2 was an independent predictor of polycythemia in young adults and Hemoglobin and hematocrit values might have diagnostic utility for assessing nocturnal hypoxia severity of OSA patients, especially in men.
Journal ArticleDOI
Clinical Validation of a Dried Blood Spot Assay for 8 Antihypertensive Drugs and 4 Active Metabolites.
Laura E J Peeters,Lida Feyz,Edon Hameli,Tom C. Zwart,Soma Bahmany,Joost Daemen,Teun van Gelder,Jorie Versmissen,Birgit C. P. Koch +8 more
TL;DR: The DBS assay is a suitable method to detect drug non-adherence, but with the exception of canrenone, the interchangeable use of plasma and DBS sampling to interpret drug quantities should be avoided.
Journal ArticleDOI
Clinicians' Perspectives on Barriers and Enablers of Optimal Prescribing in Patients with Dementia and Coexisting Conditions.
Ariel R. Green,Patricia Lee,Emily Reeve,Jennifer L. Wolff,Chi Chiung Grace Chen,Rachel Kruzan,Cynthia M. Boyd +6 more
TL;DR: Clinicians identified numerous barriers to and some facilitators of optimizing prescribing in people with dementia, which included the lack of data on efficacy and safety of most medications in peopleWith dementia, difficulty assessing medication effects in an individual patient, and the perception that stopping medications is seen as “giving up.”
Journal ArticleDOI
Prediction of Prehypertenison and Hypertension Based on Anthropometry, Blood Parameters, and Spirometry
Byeong Mun Heo,Keun Ho Ryu +1 more
TL;DR: The findings of this study can be used as a large-scale screening tool for controlling and managing hypertension.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated, and empathy builds trust and is a potent motivator.
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The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TL;DR: The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.
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