2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Paul K. Whelton,Robert M. Carey,Wilbert S. Aronow,Donald E. Casey,Karen J. Collins,Cheryl Dennison Himmelfarb,Sondra M. DePalma,Samuel S. Gidding,Kenneth Jamerson,Daniel W. Jones,Eric J. MacLaughlin,Paul Muntner,Bruce Ovbiagele,Sidney C. Smith,Crystal C. Spencer,Randall S. Stafford,Sandra J. Taler,Randal J. Thomas,Kim A. Williams,Jeff D. Williamson,Jackson T. Wright +20 more
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Since 1980, the American College of Cardiology and American Heart Association have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health.Abstract:
Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisoryread more
Citations
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Average Clinician-Measured Blood Pressures and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease in the EXAMINE Trial.
William B. White,Fatima Jalil,William C. Cushman,George L. Bakris,Richard M. Bergenstal,Simon Heller,Yuyin Liu,Cyrus R. Mehta,Faiez Zannad,Christopher P. Cannon +9 more
TL;DR: Average BPs <130/80 mm Hg were associated with worsened cardiovascular outcomes, and data suggest that intensive control of BP in patients with type 2 diabetes mellitus and ischemic heart disease should be evaluated in a prospective randomized trial.
Journal ArticleDOI
Critical role of Interleukin 21 and T follicular helper cells in hypertension and vascular dysfunction.
Bethany L. Dale,Arvind K. Pandey,Yuhan Chen,Charles D Smart,Fanny Laroumanie,Mingfang Ao,Liang Xiao,Anna Dikalova,Sergey Dikalov,Fernando Elijovich,Jason D. Foss,Natalia R. Barbaro,Justin P Van Beusecum,Serpil Muge Deger,Aseel Alsouqi,Hana A. Itani,Allison E. Norlander,Matthew R Alexander,Shilin Zhao,T. Alp Ikizler,Holly M. Scott Algood,Holly M. Scott Algood,Meena S. Madhur +22 more
TL;DR: It is shown in humans that peripheral blood T cell production of IL21 correlates with systolic BP and IL17A production, and data suggest that IL21 may be a novel therapeutic target for the treatment of hypertension and its micro- and macrovascular complications.
Journal ArticleDOI
(-)-Epicatechin Reduces the Blood Pressure of Young Borderline Hypertensive Rats During the Post-Treatment Period.
TL;DR: While Epi-induced a decrease of the rats’ BP persisted for two weeks post treatment, continuous Epi treatments seem to be necessary for maintaining elevated NO production as well as redox balance in the heart and aorta without changes in the NOSs, Nrf2, and PPAR-γ gene expressions.
Journal ArticleDOI
Brief recommendations for participation in competitive sports of athletes with arterial hypertension: Summary of a Position Statement from the Sports Cardiology Section of the European Association of Preventive Cardiology (EAPC)
Josef Niebauer,Mats Börjesson,F. Carré,Stefano Caselli,Paolo Palatini,Filippo M. Quattrini,Luis Serratosa,Paolo Emilio Adami,Alessandro Biffi,Axel Pressler,Hanne K Rasmusen,Christian Schmied,Frank van Buuren,Nicole Panhuyzen-Goedkoop,Erik Ekker Solberg,Martin Halle,Andre La Gerche,Michael Papadakis,Sanjay Sharma,Antonio Pelliccia +19 more
TL;DR: In this paper, the European Society of Cardiology guidelines advocate regular physical activity as a class IA recommendation for the prevention and treatment of cardiovascular disease, however, competitive athletes with arterial hypertension may be exposed to an increased risk of cardiovascular events.
Journal ArticleDOI
Trajectories of Blood Pressure Elevation Preceding Hypertension Onset: An Analysis of the Framingham Heart Study Original Cohort.
Teemu J. Niiranen,Mir Henglin,Mir Henglin,Brian Claggett,Brian Claggett,Vito M. R. Muggeo,Elizabeth L. McCabe,Elizabeth L. McCabe,Mohit Jain,Ramachandran S. Vasan,Martin G. Larson,Susan Cheng,Susan Cheng,Susan Cheng +13 more
TL;DR: A resting systolic BP that chronically exceeds the range of approximately 120 to 125 mm Hg may represent an important threshold of underlying vascular remodeling and signal incipient hypertension irrespective of age.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated, and empathy builds trust and is a potent motivator.
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The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TL;DR: The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.
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