2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Paul K. Whelton,Robert M. Carey,Wilbert S. Aronow,Donald E. Casey,Karen J. Collins,Cheryl Dennison Himmelfarb,Sondra M. DePalma,Samuel S. Gidding,Kenneth Jamerson,Daniel W. Jones,Eric J. MacLaughlin,Paul Muntner,Bruce Ovbiagele,Sidney C. Smith,Crystal C. Spencer,Randall S. Stafford,Sandra J. Taler,Randal J. Thomas,Kim A. Williams,Jeff D. Williamson,Jackson T. Wright +20 more
TLDR
Since 1980, the American College of Cardiology and American Heart Association have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health.Abstract:
Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular health. In 2013, the National Heart, Lung, and Blood Institute (NHLBI) Advisoryread more
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Cardiovascular morbidity and mortality in ankylosing spondylitis and psoriatic arthritis.
TL;DR: This work examines the contribution of anti- inflammatory therapy with nonsteroidal anti-inflammatory drugs, disease-modifying anti-rheumatic drugs, and TNF inhibitors on the cardiovascular risk profile of ankylosing spondyloarthritis patients.
Journal ArticleDOI
Blood-pressure variability in patients with obstructive sleep apnea: current perspectives.
TL;DR: Treatment of OSA slightly reduces mean 24-hour BP levels and nocturnal beat-by-beat BP variability by abolishing noCTurnal BP peaks, and in some patients OSA treatment turns a nondipping into a dipping BP profile.
Journal ArticleDOI
Primordial Prevention of High Blood Pressure in Childhood: An Opportunity Not to be Missed.
Bonita Falkner,Empar Lurbe +1 more
TL;DR: Primordial prevention of hypertension consists of strategies to maintain blood pressure in a normal range and prevent development of elevated blood pressure or hypertension.
Journal ArticleDOI
Risk Factors for CKD Progression: Overview of Findings from the CRIC Study
Mary Hannan,Sajid Ansari,Natalie Meza,Amanda H. Anderson,Anand Srivastava,Sushrut S. Waikar,Jeanne Charleston,Matthew R. Weir,Jonathan J. Taliercio,Edward Horwitz,Milda R. Saunders,Katherine Wolfrum,Harold I. Feldman,James P. Lash,Ana C. Ricardo +14 more
TL;DR: Findings from longitudinal studies evaluating risk factors associated with CKD progression in the CRIC Study are summarized, grouped into the following six thematic categories: sociodemographic and economic (sex, race/ethnicity, and nephrology care); behavioral (healthy lifestyle, diet, and sleep); genetic (apoL1, genome-wide association study); and novel factors (AKI and biomarkers of kidney injury).
Journal ArticleDOI
Kidney Damage Biomarkers and Incident Chronic Kidney Disease During Blood Pressure Reduction: A Case-Control Study.
William R. Zhang,Timothy E. Craven,Rakesh Malhotra,Alfred K. Cheung,Michel Chonchol,Paul E. Drawz,Mark J. Sarnak,Chirag R. Parikh,Michael G. Shlipak,Joachim H. Ix +9 more
TL;DR: It is hypothesized that biomarker changes among CKD case participants in the intensive group would represent benign changes in renal blood flow rather than intrinsic tissue injury, and changes in urinary biomarkers were associated with risk for incident CKD.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated, and empathy builds trust and is a potent motivator.
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The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
Julian P T Higgins,Douglas G. Altman,Peter C Gøtzsche,Peter Jüni,David Moher,Andrew D Oxman,Jelena Savović,Kenneth F. Schulz,Laura Weeks,Jonathan A C Sterne +9 more
TL;DR: The Cochrane Collaboration’s tool for assessing risk of bias aims to make the process clearer and more accurate.
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