2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
Citations
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Journal ArticleDOI
Weight loss and its influence on high-density lipoprotein cholesterol (HDL-C) concentrations: A noble clinical hesitation.
Heitor O. Santos,Carl J. Lavie +1 more
TL;DR: In this article, the relationship between obesity, weight loss, and high-density lipoprotein cholesterol (HDL-C) is poorly recognized and understood; however, there is a paradoxical link between weight loss and HDL-C levels, which can result in both increases and reductions in the concentrations of this recognized biomarker of cardiovascular health.
Journal ArticleDOI
Lipoprotein(a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options.
TL;DR: Recent data on the role of Lp(a) in the atherosclerotic process, and treatment options for patients with cardiovascular diseases are reviewed, and gene-based therapies that affect transcription and translation of apolipop protein mRNA are discussed.
Book ChapterDOI
Glycaemic Control and Vascular Complications in Diabetes Mellitus Type 2.
TL;DR: A combination of anti-atherogenic effects and hemodynamic improvements are likely explanations of the observed reduction in cardiovascular events and mortality.
Journal ArticleDOI
Lipoprotein(a), LDL-cholesterol, and hypertension: Predictors of the need for aortic valve replacement in familial hypercholesterolaemia
Leopoldo Pérez de Isla,Gerald F. Watts,Gerald F. Watts,Rodrigo Alonso,José Luis Díaz-Díaz,Ovidio Muñiz-Grijalvo,Daniel Zambón,Francisco Fuentes,Raimundo de Andrés,Teresa Padró,Jose Lopez-Miranda,Pedro Mata +11 more
TL;DR: The SAFEHEART study as mentioned in this paper investigated the frequency and predictors of severe AVS requiring aortic valve replacement (AVR) in molecularly defined patients with FH.
Journal ArticleDOI
Prognostic utility of triglyceride-rich lipoprotein-related markers in patients with coronary artery disease.
Ye-Xuan Cao,Hui-Wen Zhang,Jing-Lu Jin,Hui-Hui Liu,Yan Zhang,Rui-Xia Xu,Ying Gao,Yuan-Lin Guo,Cheng-Gang Zhu,Qi Hua,Yan-Fang Li,Raul D. Santos,Na-Qiong Wu,Jian-Jun Li +13 more
TL;DR: TRL, RLP-C, and apoC-III levels were independently associated with incident CVEs in Chinese CAD patients undergoing statin therapy, and all three TRL biomarkers improved risk reclassification.
References
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TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.
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TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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