2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
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Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia
TL;DR: In this article, a fixed-dose combination (FDC) of rosuvastatin/ezetimibe is indicated as an adjunctive therapy to diet for the management of primary hypercholesterolemia in adults in numerous countries worldwide.
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Critical Differences Between Dietary Supplement and Prescription Omega-3 Fatty Acids: A Narrative Review
TL;DR: Critical therapeutic differences among the OM-3 fatty acids are described, focusing on differences between fish oil supplements and Rx OM- 3s, to recognize critical differences between Rx and OM-1 dietary supplements to ensure appropriate use of each OM-2 product.
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Low-density Lipoprotein-Cholesterol Lowering Strategies for Prevention of Atherosclerotic Cardiovascular Disease: Focus on siRNA Treatment Targeting PCSK9 (Inclisiran)
David Sinning,Ulf Landmesser +1 more
TL;DR: SiRNA therapy targeting PCSK9 (inclisiran) applied twice a year efficiently reduced LDL-C by approximately 50% and was safe in recent phase 3 studies, and the effects of this treatment on CV outcome are currently further assessed in a large ongoing CV outcome trial.
Journal ArticleDOI
Platelet-Mimicking Therapeutic System for Noninvasive Mitigation of the Progression of Atherosclerotic Plaques.
TL;DR: Inspired by the plaque-binding ability of platelets, a biomimic photodynamic therapeutic system is designed to mitigate the progression of atherosclerotic plaques in this paper, which is composed of photosensitizer-loaded upconversion nanoparticle cores entrapped in the platelet membrane.
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Management of Obesity in Cardiovascular Practice: JACC Focus Seminar.
TL;DR: In this article, the authors emphasize that the tendency among health care professionals to amalgam all forms of obesity altogether as a single entity may contribute to such difficulties and discrepancies, and focus should be given to two prevalent subgroups of individuals: 1) patients who are overweight or moderately obese with excess visceral adipose tissue; and 2) patients with severe obesity, the latter group having distinct additional health issues related to their large body fat mass.
References
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Atherosclerosis is an Inflammatory Disease
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TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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