2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
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Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: a prospective, placebo-controlled randomized trial (EVAPORATE): interim results.
Matthew J. Budoff,Joseph B. Muhlestein,Deepak L. Bhatt,Viet T Le Pa,Viet T Le Pa,Heidi T May,Kashif Shaikh,Chandana Shekar,April Kinninger,Suvasini Lakshmanan,Sion K. Roy,John A. Tayek,John R Nelson +12 more
TL;DR: This study shows that most coronary plaque types show slowed rates of progression under the influence of statin plus Icosapent ethyl, and provides important mechanistic data in regards to the reduction in CV events in the REDUCE-IT clinical trial.
Journal ArticleDOI
2020 Update of the quality indicators for acute myocardial infarction: a position paper of the Association for Acute Cardiovascular Care: the study group for quality indicators from the ACVC and the NSTE-ACS guideline group.
Francois Schiele,Suleman Aktaa,Xavier Rossello,Ingo Ahrens,Marc J. Claeys,Jean-Philippe Collet,Jean-Philippe Collet,Keith A.A. Fox,Chris P Gale,Kurt Huber,Zaza Iakobishvili,Alan Keys,Ekaterini Lambrinou,Sergio Leonardi,Maddalena Lettino,Frederick A. Masoudi,Susanna Price,Tom Quinn,Eva Swahn,Holger Thiele,Adam Timmis,Marco Tubaro,Christiaan J. Vrints,David Walker,Héctor Bueno,Sigrun Halvorsen,Tomas Jernberg,Jarle Jortveit,Mai Blöndal,Borja Ibanez,Christian Hassager +30 more
TL;DR: In this article, the ESC developed a set of quality indicators for acute myocardial infarction (AMI), which have been evaluated at national and international levels and across different populations.
Journal ArticleDOI
Lower Extremity Peripheral Artery Disease Without Chronic Limb-Threatening Ischemia: A Review
TL;DR: The ankle-brachial index (ABI) is a ratio of Doppler-recorded pressures in the dorsalis pedis and/or posterior tibial artery in each leg to brachial artery pressures as discussed by the authors.
Journal ArticleDOI
Efficacy of Evolocumab on Cardiovascular Outcomes in Patients With Recent Myocardial Infarction: A Prespecified Secondary Analysis From the FOURIER Trial.
Baris Gencer,Baris Gencer,François Mach,Sabina A. Murphy,Gaetano M. De Ferrari,Kurt Huber,Basil S. Lewis,Jorge Ferreira,Christopher E. Kurtz,Huei Wang,Narimon Honarpour,Anthony C Keech,Peter S. Sever,Terje R. Pedersen,Marc S. Sabatine,Robert P. Giugliano +15 more
TL;DR: A prespecified secondary analysis of the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) trial, in which 27 564 patients with atherosclerotic cardiovascular disease treated with a statin were randomized to evolocumab vs placebo, found patients with a recent MI were at higher risk of cardiovascular events.
Journal ArticleDOI
Role of Bempedoic Acid in Clinical Practice
Christie M. Ballantyne,Harold E. Bays,Alberico L. Catapano,Anne C. Goldberg,Kausik K. Ray,Joseph J. Saseen +5 more
TL;DR: Bempedoic acid, a new class of agent, is a prodrug converted to bempedoyl-CoA by very long-chain acyl CoA synthetase 1, an enzyme with high expression in the liver but that is undetectable in the skeletal muscle.
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TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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