2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
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The Long-Term Dietitian and Psychological Support of Obese Patients Who Have Reduced Their Weight Allows Them to Maintain the Effects.
TL;DR: In this article, a randomized controlled study was conducted to explore the efficacy of following dietary and psychological support in a group of 36 obese individuals, which included some elements of Ten Top Tips (TTT), cognitive behavioral therapy (CBT), motivational interviewing (MI), nutritional education and assessment of the level of physical activity.
Journal ArticleDOI
Low-density lipoprotein particles in atherosclerosis
TL;DR: The atherogenic mechanisms of action of LDL are outlined by focusing on sdLDL and ox-LDL, the methods used for measurement of LDL subclasses are summarized, and advances in LDL-lowering therapies using statins and PCSK9i are concluded.
Journal ArticleDOI
Low LDL-C levels are associated with risk of mortality in a Chinese cohort study
Jieming Lu,Mengyin Wu,Zongming Yang,Yao Zhu,Die Li,Zhebin Yu,Peng Shen,Mengling Tang,Mingjuan Jin,Hongbo Lin,Liming Shui,Kun Chen,Jianbing Wang +12 more
TL;DR: In this article, the association of LDL-C level with risk of mortality using a propensity-score weighting method in a Chinese population, based on the health examination data was examined, and the authors used Cox proportional hazard regression models with all-cause and cause-specific mortality as the dependent variables to estimate hazard ratios and 95% confidence intervals.
Journal ArticleDOI
Association between PCSK9 Levels and Markers of Inflammation, Oxidative Stress, and Endothelial Dysfunction in a Population of Nondialysis Chronic Kidney Disease Patients
Evangelia Dounousi,Constantinos C. Tellis,Paraskevi Pavlakou,Anila Duni,Vasillios Liakopoulos,Patrick B. Mark,Aikaterini Papagianni,Alexandros D. Tselepis +7 more
TL;DR: In this paper, the authors investigated the possible association of serum PCSK9 levels with markers of inflammation, oxidative stress, and endothelial damage in patients with chronic kidney disease (CKD).
Journal ArticleDOI
Efficacy and Safety of PCSK9 Monoclonal Antibodies in Patients at High Cardiovascular Risk: An Updated Systematic Review and Meta-Analysis of 32 Randomized Controlled Trials
Guangyan Mu,Qian Xiang,Shuang Zhou,Zhiyan Liu,Litong Qi,Jie Jiang,Yanjun Gong,Qiufen Xie,Zining Wang,Hanxu Zhang,Yong Huo,Yimin Cui +11 more
TL;DR: Both alirocumab and evolocumab are well tolerated and can greatly improve lipid profiles for patients at high cardiovascular risk and significantly reduce the risk of nonfatal MACEs in patients with previous cardiovascular events.
References
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TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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