2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
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Standards of Medical Care in Diabetes
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References
More filters
Journal ArticleDOI
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Daniel I. Swerdlow,David Preiss,Karoline Kuchenbaecker,Michael V. Holmes,Jorgen Engmann,Tina Shah,Reecha Sofat,Stefan Stender,Paul C. D. Johnson,Robert A. Scott,Maarten Leusink,Niek Verweij,Stephen J. Sharp,Yiran Guo,Claudia Giambartolomei,Christina Chung,Anne Peasey,Antoinette Amuzu,KaWah Li,Jutta Palmen,Philip N. Howard,Jackie A. Cooper,Fotios Drenos,Yun Li,Gordon D.O. Lowe,John Gallacher,Marlene C. W. Stewart,Ioanna Tzoulaki,Sarah G. Buxbaum,Daphne L. van der A,Nita G. Forouhi,N. Charlotte Onland-Moret,Yvonne T. van der Schouw,Renate B. Schnabel,Jaroslav A. Hubacek,Ruzena Kubinova,Migle Baceviciene,Abdonas Tamosiunas,Andrzej Pajak,Romanvan Topor-Madry,Urszula Stepaniak,Sofia Malyutina,Damiano Baldassarre,Bengt Sennblad,Elena Tremoli,Ulf de Faire,Fabrizio Veglia,Ian Ford,J. Wouter Jukema,Rudi G. J. Westendorp,Gert J. de Borst,Pim A. de Jong,Ale Algra,Wilko Spiering,Anke H. Maitland-van der Zee,Olaf H. Klungel,Anthonius de Boer,Pieter A. Doevendans,Charles B. Eaton,Jennifer G. Robinson,David Duggan,John Kjekshus,John R. Downs,Antonio M. Gotto,Anthony C Keech,Roberto Marchioli,Gianni Tognoni,Peter S. Sever,Neil R Poulter,David D. Waters,Terje R. Pedersen,Pierre Amarenco,Haruo Nakamura,John J.V. McMurray,James Lewsey,Daniel I. Chasman,Paul M. Ridker,Aldo P. Maggioni,Luigi Tavazzi,Kausik K. Ray,Sreenivasa Rao Kondapally Seshasai,JoAnn E. Manson,Jackie F. Price,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,George Davey Smith,Yoav Ben-Shlomo,Pamela J. Schreiner,Myriam Fornage,David S. Siscovick,Mary Cushman,Meena Kumari,Nicholas J. Wareham,W M Monique Verschuren,Susan Redline,Sanjay R. Patel,John C. Whittaker,Anders Hamsten,Joseph A.C. Delaney,Caroline Dale,Tom R. Gaunt,Andrew Wong,Diana Kuh,Rebecca Hardy,Sekar Kathiresan,Berta Almoguera Castillo,Pim van der Harst,Eric J. Brunner,Anne Tybjærg-Hansen,Michael Marmot,Ronald M. Krauss,Michael Y. Tsai,Josef Coresh,Ron C. Hoogeveen,Bruce M. Psaty,Leslie A. Lange,Hakon Hakonarson,Frank Dudbridge,Steve E. Humphries,Philippa J. Talmud,Mika Kivimäki,Nicholas J. Timpson,Claudia Langenberg,Folkert W. Asselbergs,Mikhail Voevoda,Martin Bobak,Hynek Pikhart,James G. Wilson,Alexander P. Reiner,Brendan J. Keating,Aroon D. Hingorani,Naveed Sattar +132 more
TL;DR: The increased risk of type 2 diabetes noted with statins is at least partially explained by HMGCR inhibition.
Journal ArticleDOI
Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials
Nicholas J. Viney,Julian C. van Capelleveen,Richard S. Geary,Shuting Xia,Joseph A. Tami,Rosie Z. Yu,Santica M. Marcovina,Steven G. Hughes,Mark J. Graham,Rosanne M. Crooke,Stanley T. Crooke,Joseph L. Witztum,Erik S.G. Stroes,Sotirios Tsimikas,Sotirios Tsimikas +14 more
TL;DR: A phase 1/2a first-in-man trial and a phase 2 trial aimed to assess the efficacy, safety, and tolerability of two unique antisense oligonucleotides designed to lower Lp(a) concentrations.
Journal ArticleDOI
Reduction in cardiovascular events after vascular surgery with atorvastatin: a randomized trial
Anai E.S. Durazzo,Fabio Santana Machado,Dimas Ikeoka,Claudia Bernoche,Maristela C. Monachini,Pedro Puech-Leão,Bruno Caramelli +6 more
TL;DR: Short-term treatment with atorvastatin significantly reduces the incidence of major adverse cardiovascular events after vascular surgery, and shows a significant decrease in the rate of cardiac events.
Journal ArticleDOI
Abdominal aortic aneurysm : Pathogenesis and implications for management
TL;DR: Clear level 1 evidence for drug treatments of AAA is presently lacking; however, animal and human in vitro studies suggest that medication targeted at reducing inflammation and proteolysis are most likely to be beneficial, with limited data to support the use of statins, Angiotensin II inhibitors, and macrolides.
Journal ArticleDOI
Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease
A. Michael Lincoff,Stephen J. Nicholls,Jeffrey S. Riesmeyer,Philip J. Barter,H. Bryan Brewer,Keith A.A. Fox,C. Michael Gibson,Christopher B. Granger,Venu Menon,G. Montalescot,Daniel J. Rader,Alan R. Tall,Ellen McErlean,Kathy Wolski,Giacomo Ruotolo,Burkhard Vangerow,Govinda Weerakkody,Shaun G Goodman,Diego Conde,Darren K. McGuire,Jose C. Nicolau,Jose L. Leiva-Pons,Yves Pesant,Weimin Li,David Kandath,Simon Kouz,Naeem Tahirkheli,Denise Mason,Steven E. Nissen +28 more
TL;DR: Treatment with evacetrapib did not result in a lower rate of cardiovascular events than placebo among patients with high‐risk vascular disease, and had favorable effects on established lipid biomarkers.
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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular riskThe Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)
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