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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)
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This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.

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Citations
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LDL subclass lipidomics in atherogenic dyslipidemia: effect of statin therapy on bioactive lipids and dense LDL.

TL;DR: Bioactive lipids may constitute biomarkers for the cardiometabolic risk associated with specific LDL subclasses in atherogenic dyslipidemia at baseline, and with residual risk on statin therapy, consistent with reduction in cardiovascular risk.
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The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.

TL;DR: Several foods distinctly modify LDL cholesterol levels, and the results may aid future guidelines and dietary advice for hypercholesterolemia.
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Why patients with familial hypercholesterolemia are at high cardiovascular risk? Beyond LDL-C levels.

TL;DR: The overall CVD risk burden of the FH population is discussed, the prognostic impact of several traditional and emerging predictors ofCVD risk are revised, and the role of specific tools to stratify CVDrisk in FH patients is provided in order to ensure them a more personalized treatment approach.
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Supracardiac atherosclerosis in embolic stroke of undetermined source: the underestimated source

TL;DR: The evidence is presented which points towards a major aetiological association between atherosclerotic plaques and ESUS, the imaging features which may aid to identify plaques more likely to be associated with ESUS are summarized, strategies to reduce the associated stroke risk are discussed, and the rationale for future research is highlighted.
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The dawn of a new era of targeted lipid-lowering therapies.

TL;DR: This article reviews this progress offering insight into novel biological and therapeutic discoveries, and places them into a practical patient care perspective.
References
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Journal ArticleDOI

Atherosclerosis — An Inflammatory Disease

TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal Article

Atherosclerosis is an Inflammatory Disease

TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.

Standards of Medical Care in Diabetes

TL;DR: These standards of care are intended to provide clinicians, patients, researchers, payors, and other interested individuals with the components of diabetes care, treatment goals, and tools to evaluate the quality of care.
Related Papers (5)

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular riskThe Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)

François Mach, +120 more