2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
Citations
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Statins and All‐Cause Mortality in Patients Undergoing Hemodialysis
TL;DR: The results showed that in adult patients undergoing maintenance hemodialysis, statin therapy, preferably combined with ezetimibe, was associated with a lower risk of all‐cause mortality.
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Lipid Management in Patients Presenting With Acute Coronary Syndromes: A Review
Bimmer E. Claessen,Paul Guedeney,Paul Guedeney,C. Michael Gibson,Dominick J. Angiolillo,Davide Cao,Norman E. Lepor,Roxana Mehran +7 more
TL;DR: The current state of evidence on lipid management in patients presenting with ACS is detailed, directions for identification of patients who may benefit from early escalation of lipid‐lowering therapy are provided, and a treatment algorithm aimed at attaining guideline‐recommended low‐density lipoprotein cholesterol levels is proposed.
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The Road to Approval: a Perspective on the Role of Icosapent Ethyl in Cardiovascular Risk Reduction.
TL;DR: As first of its class to be approved, icosapent ethyl offers a new option to further reduce cardiovascular risks in patients already treated with maximally tolerated statins.
Journal ArticleDOI
Reasons Why Combination Therapy Should Be the New Standard of Care to Achieve the LDL-Cholesterol Targets : Lipid-lowering combination therapy.
TL;DR: New RCT, meta-analysis, and Mendelian randomization data, support that the main determinant of risk reduction is the absolute LDL reduction regardless of LLT, and the "high-intensity statin therapy” concept should be substituted by “high- intensity lipid lowering therapy.”
Journal ArticleDOI
The extended lipid panel assay: a clinically-deployed high-throughput nuclear magnetic resonance method for the simultaneous measurement of lipids and Apolipoprotein B
Erwin Garcia,Dennis W. Bennett,Margery A. Connelly,Elias J. Jeyarajah,Franklin C. Warf,Irina Shalaurova,Steven P. Matyus,Justyna Wolak-Dinsmore,David N. Oskardmay,Randolph M. Young,Maureen Sampson,Alan T. Remaley,James D. Otvos +12 more
TL;DR: Extensive assay performance evaluations validate that the NMR ELP assay is efficient, robust, and substantially equivalent to standard chemistry assays for the clinical measurement of lipids and apoB.
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TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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