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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)
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This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.

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Citations
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Autocrine effects of PCSK9 on cardiomyocytes

TL;DR: The data show that cardiomyocytes express and release PCSK9 that acts in an autocrine way on carduomyocytes and impairs their function.
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Evaluation of a new equation for estimating low-density lipoprotein cholesterol through the comparison with various recommended methods.

TL;DR: The Sampson equation may represent a cost-efficient alternative for calculating LDL in clinical laboratories and with a direct LDL method, and with the Friedewald and Martin-Hopkins equations.
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An Update on Coronary Artery Calcium Interpretation at Chest and Cardiac CT

TL;DR: In this paper, the authors present a CAC interpretation on traditional electrocardiographically gated scans and nongated thoracic scans, including the absolute Agatston score and the age, sex, and race-specific CAC percentile.
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Association of Low‐Density Lipoprotein Cholesterol Levels with More than 20‐Year Risk of Cardiovascular and All‐Cause Mortality in the General Population

TL;DR: Very low and very high LDL-C levels were associated with increased risk of CVD mortality in the general population as discussed by the authors , however, they did not reveal the optimal range of low-density lipoprotein cholesterol (LDL-C) levels for CVD health.
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Bempedoic acid: A promising novel agent for LDL-C lowering

TL;DR: Bempedoic acid is currently being evaluated in a cardiovascular outcomes trial to evaluate its effect on major cardiovascular events in patients with or at high risk for cardiovascular disease and with statin intolerance.
References
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Journal ArticleDOI

Atherosclerosis — An Inflammatory Disease

TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal Article

Atherosclerosis is an Inflammatory Disease

TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.

Standards of Medical Care in Diabetes

TL;DR: These standards of care are intended to provide clinicians, patients, researchers, payors, and other interested individuals with the components of diabetes care, treatment goals, and tools to evaluate the quality of care.
Related Papers (5)

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular riskThe Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)

François Mach, +120 more