2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
Alison Halliday,Colin Baigent,François Mach,Borislava Mihaylova,Borislava Mihaylova,Brian A. Ference +5 more
TLDR
Authors/Task Force Members (François Macha, Colin Baigentb,∗∗,2, Alberico L. Catapanoc), ESC Committee for Practice Guidelines (CPG) (Stephan Windeckeraa), ESC National Cardiac Societies (Djamaleddine Nibouchean, Parounak H. Patelcl)About:
This article is published in Atherosclerosis.The article was published on 2019-09-02 and is currently open access. It has received 2972 citations till now. The article focuses on the topics: Lipid modification & Very low-density lipoprotein.read more
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Cardiovascular risk assessment: The foundation of preventive cardiology.
TL;DR: While current techniques best predict long-term risk of CVD events, biomarkers strategies are being developed to predict near-term events, and other imaging techniques such as coronary CT angiography and vascular MRI hold promise to identify vulnerable plaque.
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Low-Density Lipoprotein Cholesterol Level cannot be too Low: Considerations from Clinical Trials, Human Genetics, and Biology.
TL;DR: The idea that the authors need to rethink what is the optimal range of LDL cholesterol level, instead of “normal” or “average” range is provided, based on a series of evidence from clinical trials, human genetics, and biology.
Journal ArticleDOI
Cost-effectiveness of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab in patients with a history of myocardial infarction in Sweden
Ulf Landmesser,Peter Lindgren,Peter Lindgren,Emil Hagström,Ben van Hout,Guillermo Villa,Peter Pemberton-Ross,Jorge Arellano,Maria Eriksson Svensson,Maria Eriksson Svensson,M Sibartie,Gregg C. Fonarow +11 more
TL;DR: Proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab added to maximum tolerated dose of statin and ezetimibe may be considered cost-effective at its list price for minimum LDL-C levels, with ICERs below the accepted willingness-to-pay threshold in Sweden.
Journal ArticleDOI
Beyond Lipid-Lowering: Effects of Statins on Cardiovascular and Cerebrovascular Diseases and Cancer
TL;DR: A review of the effect of statins on cardiovascular and cerebrovascular diseases and cancer is presented in this paper , focusing on the aspect of "beyond lipid-lowering".
Journal ArticleDOI
Non-HDL-C/TG ratio indicates significant underestimation of calculated low-density lipoprotein cholesterol (LDL-C) better than TG level: a study on the reliability of mathematical formulas used for LDL-C estimation.
Agnieszka Ćwiklińska,Ewa Wieczorek,Anna Gliwińska,Marta Marcinkowska,Monika Czaplińska,Agnieszka Mickiewicz,Agnieszka Kuchta,Barbara Kortas-Stempak,Marcin Gruchała,Alicja Dębska-Ślizień,Ewa Król,Maciej Jankowski +11 more
TL;DR: In this paper, the authors compared the measured LDL-C with LDL-Cs as calculated by the Friedewald, Martin/Hopkins, Vujovic, and Sampson formulas with regard to triglyceride (TG), LDL-c and non-high-density lipoprotein cholesterol (non-HDL-C)/TG ratio.
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TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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