Journal ArticleDOI
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression
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This article is published in Yearbook of Gastroenterology.The article was published on 2010-01-01. It has received 584 citations till now. The article focuses on the topics: Hepatitis C virus.read more
Citations
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Update on the Diagnosis a Hepatitis C
Arun Jesudian,Ira M. Jacobson +1 more
TL;DR: H epatitis C virus (HCV) infection is a national and global public health concern, and direct detection of HCV RNA has largely replaced recombinant immunoblot assay, which previously had been used to identify false-positive anti-HCV results.
Safety and Efficacy of Elbasvir/Grazoprevir in Patients With Hepatitis C Virus Infection and Compensated Cirrhosis: An Integrated Analysis
Ira M. Jacobsen,Eric Lawitz,Paul Y. Kwo,Christophe Hézode,Cheng Yuan Peng,Anita Y. M. Howe,Peggy Hwang,Janice Wahl,Michael N. Robertson,Eliav Barr,Barbara Haber +10 more
TL;DR: In this article, the effects of the direct-acting antiviral agents elbasvir and grazoprevir in patients with HCV infection and compensated cirrhosis, combining data from 6 clinical trials, were analyzed.
Journal Article
Cribado, diagnóstico y tratamiento de la hepatitis por virus C en la práctica clínica
TL;DR: It is necessary to increase the number of diagnosed patients, linking them to adequate management and treatment, and raising treatment rates will increase the percentage of cured patients, reducing the burden of disease.
Journal ArticleDOI
Diabetes Mellitus in Hepatitis C Patients Presenting to Tertiary Care Facility, Nawabshah
TL;DR: Type 2 diabetes mellitus was observed high among hepatitis C positive patients and significant correlation of liver cirrhosis, gender, and age was observed with diabetes among HCV patients, while no significant correlation was found with duration of HCV.
Étude structurale et fonctionnelle de la protéine Core du virus de l'hépatite C
TL;DR: It was demonstrated in the laboratory that the first half of this protein was sufficient to generate, both in vivo and in vitro, the assembly of the viral capsid, and it was established that the N-terminal half of the Core protein is a member of the intrinsically unstructured protein family (IUP).
References
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Journal ArticleDOI
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression
TL;DR: Prevalence of hepatitis C cirrhosis and its complications will continue to increase through the next decade and will mostly affect those older than 60 years of age, but wider application of antiviral treatment and better responses with new agents could significantly reduce the impact of this disease in coming years.
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