Journal ArticleDOI
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression
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This article is published in Yearbook of Gastroenterology.The article was published on 2010-01-01. It has received 584 citations till now. The article focuses on the topics: Hepatitis C virus.read more
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Cost-Utility of Elbasvir/Grazoprevir in Patients with Chronic Hepatitis C Genotype 1 Infection.
TL;DR: Compared with other oral direct-acting antiviral agents, EBR/GZR ± RBV was the economically dominant regimen for treating GT1a noncirrhotic and GT1b TN cirrhotic patients, and was cost saving in all other populations.
Journal ArticleDOI
Benzhydrylpiperazine compounds inhibit cholesterol-dependent cellular entry of hepatitis C virus
TL;DR: The two most potent hits, hydroxyzine and chlorcyclizine, belong to the family of benzhydrylpiperazines and were found to inhibit the entry of cell culture-produced HCV with IC50 values of 19 and 2.3 nM, respectively, and therapeutic indices of >500 and >6500.
Journal ArticleDOI
Evidence for association between hepatitis C virus and Parkinson’s disease
Abdelrahman Ibrahim Abushouk,Mostafa Wanees Ahmed El-Husseny,Mayar Magdy,Ammar Ismail,Attia O. Attia,Hussien Ahmed,Ravikishore Pallanti,Ahmed Negida +7 more
TL;DR: A comprehensive review on the possible association between HCV infection and PD is provided and recommendations for further research and practice in this regard are highlighted.
Journal ArticleDOI
Liver Diseases and Long Non-Coding RNAs: New Insight and Perspective.
Luca Quagliata,Luigi Terracciano +1 more
TL;DR: A review of liver disease-relevant long non-coding RNAs (lncRNAs) can be found in this article, where the authors discuss in detail several examples.
Journal ArticleDOI
The Impact of Direct-acting Antiviral Therapy for Hepatitis C on Hepatocellular Carcinoma Risk
TL;DR: Recent studies provide evidence that DAA-induced SVR reduces HCC risk, and patients with pre-existing cirrhosis require ongoing surveillance even after SVR is achieved.
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Journal ArticleDOI
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression
TL;DR: Prevalence of hepatitis C cirrhosis and its complications will continue to increase through the next decade and will mostly affect those older than 60 years of age, but wider application of antiviral treatment and better responses with new agents could significantly reduce the impact of this disease in coming years.
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