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Journal ArticleDOI

Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression

D.M. Harnois
- 01 Jan 2010 - 
- Vol. 2010, pp 233-234
About: 
This article is published in Yearbook of Gastroenterology.The article was published on 2010-01-01. It has received 584 citations till now. The article focuses on the topics: Hepatitis C virus.

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Citations
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Journal ArticleDOI

Moderate, excessive or heavy alcohol consumption: each is significantly associated with increased mortality in patients with chronic hepatitis C.

Zobair M. Younossi, +5 more
- 01 Apr 2013 - 
TL;DR: The impact of moderate alcohol consumption on long‐term outcomes of chronic hepatitis C (CH‐C) infected patients remains controversial.
Journal ArticleDOI

Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study.

Bhagwat Prasad, +14 more
- 01 Jan 2018 - 
TL;DR: Protein abundance data, combined with PBPK modeling and simulation, can be a powerful tool to predict drug disposition in special populations and integration of UGT2B7 abundance in cirrhotic livers into the Child Pugh C model of Simcyp improved the prediction of zidovudine and morphine PK in subjects with Child P Hugh C liver cirrhosis.
Journal ArticleDOI

Interferon-free combination therapies for the treatment of hepatitis C: current insights

Jacinta A Holmes, +1 more
- 02 Nov 2015 - 
TL;DR: A review of the different classes of DAAs and the various combinations that are in advanced development for the treatment of chronic HCV infection and will focus on the different regimens in specific patient populations.
Journal ArticleDOI

Expected and Actual Case Ascertainment and Treatment Rates for Children Infected with Hepatitis C in Florida and the United States: Epidemiologic Evidence from Statewide and Nationwide Surveys

Aymin Delgado-Borrego, +13 more
- 01 Nov 2012 - 
TL;DR: The identification of children infected with HCV in the nation as a whole is grossly inadequate and in Florida, less than 2% of children identified receive treatment, and in the United States, only 4.9% of the expected cases have been identified.
Journal ArticleDOI

17β-estradiol inhibits the production of infectious particles of hepatitis C virus.

Kazumi Hayashida, +5 more
- 01 Nov 2010 - 
TL;DR: The present results suggest that the most potent physiological estrogen, E2, inhibits the production of HCV infectious particles in an ERα–dependent manner.
References
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Journal ArticleDOI

Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression

Gary L. Davis, +4 more
- 01 Feb 2010 - 
TL;DR: Prevalence of hepatitis C cirrhosis and its complications will continue to increase through the next decade and will mostly affect those older than 60 years of age, but wider application of antiviral treatment and better responses with new agents could significantly reduce the impact of this disease in coming years.
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Fernando Herz Wolff, +11 more
- 05 May 2010 - 

Human immunodeficiency virus/hepatits C virus coinfection in Spain: elimination Is feasible, but the burden of residual cirrhosis will be significant

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