Journal ArticleDOI
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression
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This article is published in Yearbook of Gastroenterology.The article was published on 2010-01-01. It has received 584 citations till now. The article focuses on the topics: Hepatitis C virus.read more
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A nationwide seroepidemiology of hepatitis C virus infection in South Korea
Do Young Kim,In Hee Kim,Sook Hyang Jeong,Yong Kyun Cho,Joon Lee,Young-Joo Jin,Don Lee,Dong Jin Suh,Kwang Hyub Han,Neung Hwa Park,Ha Yan Kang,Young Kul Jung,Young Seok Kim,Kyung-Ah Kim,Youn Jae Lee,Byung Seok Lee,Hyung Joon Yim,Heon Ju Lee,Soon Koo Baik,Won Young Tak,Sun Jae Lee,Woo Jin Chung,Sung Kyu Choi,Eun Young Cho,Jeong Heo,Dong Joon Kim,Byung-Cheol Song,Man Woo Kim,Jun Lee,Hee Bok Chae,Dae Hee Choi,Hwa Young Choi,Moran Ki +32 more
TL;DR: The aim of this study was to reveal nationwide seroprevalence of HCV infection in South Korea by a large‐scale survey.
Journal ArticleDOI
The Changing Epidemiology of Primary Liver Cancer
TL;DR: While there has been progress in combating the effects of some risk factors, the increasing prevalence of others poses a major threat to attempts to tackle the rising incidence of liver cancer globally.
Journal ArticleDOI
Safety and Efficacy of Elbasvir/Grazoprevir in Patients With Hepatitis C Virus Infection and Compensated Cirrhosis: An Integrated Analysis
Ira M. Jacobson,Eric Lawitz,Paul Y. Kwo,Christophe Hézode,Cheng Yuan Peng,Anita Y. M. Howe,Peggy Hwang,Janice Wahl,Michael N. Robertson,Eliav Barr,Barbara Haber +10 more
TL;DR: Baseline tests for resistance-associated substitutions (RASs) led to an individualized approach for selecting treatment duration and established a need for ribavirin for patients with HCV genotype 1a infection and RASs, regardless of treatment history.
Journal ArticleDOI
Hepatitis C virus control among persons who inject drugs requires overcoming barriers to care
Marija Zeremski,Jon E. Zibbell,Anthony D. Martinez,Steven Kritz,Bryce D. Smith,Andrew H. Talal +5 more
TL;DR: It is advocated that multidisciplinary approaches that utilize health care practitioners from a wide range of specialties, as well as co-localization of medical services, are strategies likely to result in increased numbers of PWID entering into HCV management.
Journal ArticleDOI
Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis
Jianping Li,Yan Gao,Shifeng Chu,Zhao Zhang,Cong-Yuan Xia,Zheng Mou,Xiu-Yun Song,Wen-bin He,Xiao-Feng Guo,Nai-Hong Chen +9 more
TL;DR: Rg1 exerts protective effects in a rat model of alcohol- and CCl4-induced hepatic fibrosis via promoting the nuclear translocation of Nrf2 and expression of antioxidant enzymes.
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Journal ArticleDOI
Aging of Hepatitis C Virus (HCV)-Infected Persons in the United States: A Multiple Cohort Model of HCV Prevalence and Disease Progression
TL;DR: Prevalence of hepatitis C cirrhosis and its complications will continue to increase through the next decade and will mostly affect those older than 60 years of age, but wider application of antiviral treatment and better responses with new agents could significantly reduce the impact of this disease in coming years.
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