Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Asymmetric addition of diethylzinc to aldehydes catalyzed by β-amino alcohols derived from limonene oxide
TL;DR: A series of β-amino alcohols, conveniently prepared from limonene oxide, were evaluated as catalysts for the enantioselective addition of dialkylzinc to benzaldehyde.
Journal ArticleDOI
New 1,3-amino alcohols derived from ketopinic acid and their application in catalytic enantioselective reduction of prochiral ketones
TL;DR: In this article, the enantioselective borane reduction of prochiral ketones catalyzed by the BORANE complex of exo-4 was examined.
Journal ArticleDOI
Self and nonself recognition of chiral catalysts: The origin of nonlinear effects in the amino‐alcohol catalyzed asymmetric addition of diorganozincs to aldehydes
TL;DR: The salient features of asymmetric catalysis have been clarified on the basis of molecular weight measurements, NMR and X-ray crystallographic studies of organozinc complexes, and kinetic experiments, as well as computer-aided quantitative analysis.
Journal ArticleDOI
Ionic Tags in Catalyst Optimization: Beyond Catalyst Recycling
Marco Lombardo,Claudio Trombini +1 more
TL;DR: In this article, a working hypothesis has been developed as a basis for further investigation and testing; a decrease of the free-energy barrier is frequently observed as the result of an interplay of coulombic and steric interactions between developing charges in a polar transition state and the tag's ion pair.
Journal ArticleDOI
Enantioselective addition of dimethylzinc to aldehydes catalyzed by N-substituted mandelamide-Ti(IV) complexes
TL;DR: Amides derived from (S )-(+)-mandelic acid in the presence of titanium isopropoxide catalyze the enantioselective addition of dimethylzinc to aromatic aldehydes with good yields and ee up to 90% as mentioned in this paper.
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