Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Enantiomerically pure α-pinene derivatives from material of 65% enantiomeric purity. Part 1: Di[3α-(2α-hydroxy)pinane]amine ☆
Stanislaw Wojciech Markowicz,Katarzyna Pokrzeptowicz,Janina Karolak-Wojciechowska,Robert Czylkowski,Jan Omelańczuk,Agata Sobczak +5 more
TL;DR: By making use of differences in the physical properties of crystallographically different heteroenantiomeric racemic compounds and pure enantiomers, a convenient method for the preparation of enantiomerically pure 2α-hydroxypinan-3-one and its oxime was developed.
Journal ArticleDOI
α-Hydroxy carboxylic acids: new ligands for diethylzinc additions to aldehydes
Tomasz Bauer,Joanna Tarasiuk +1 more
TL;DR: The first examples of the enantioselective titanium-mediated diethylzinc additions to benzaldehyde catalyzed by optically active α-hydroxy acids are presented in this paper.
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An efficient method for catalytic enantioselective addition of diethylzinc to aryl aldehydes by a C2-symmetric chiral imino alcohol
TL;DR: In this paper, the enantioselective alkylation of aryl aldehydes with diethylzinc in the presence of a C2-symmetric chiral ligand derived from 2-hydroxy-3-pinanone was achieved at room temperature with high enantiomeric excesses.
Journal ArticleDOI
The role of the substitution pattern on the catalytic activity of chiral bridgehead norbornane-derived β-amino alcohols
Antonio García Martínez,Enrique Teso Vilar,Amelia García Fraile,Santiago de la Moya Cerero,Paloma Martínez-Ruiz +4 more
TL;DR: In this article, the enantioselective addition of diethylzinc to benzaldehyde has been used as standard procedure to test a series of new chiral catalysts derived from norbornane framework.
Journal ArticleDOI
One-pot, Three-component Synthesis of Fully Substituted 1,3,4-Oxadiazole Derivatives from (N-Isocyanoimino)triphenylphosphorane, Aromatic Carboxylic acids and (1R)-()-Campherchinon
TL;DR: In this article, a multicomponent reactions have appeared as anefficient and powerful tool in modern synthetic organicchemistry due to their valued features such as atom economy, straightforward reaction design, and the opportunity toconstruct target compounds by the introduction of several diversity elements in a single chemical event.
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