Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Zn(ODf)2: preparation and application in asymmetric alkynylation of aldehydes.
TL;DR: A new Lewis acid, Zn(ODf)2, was first prepared from commercially available 3,3,4,4-tetrafluoro[1,2]oxathietane 2,2-dioxide in four steps with 56% yields and also was applied to catalyze highly enantioselective alkynylation of aldehydes.
Journal ArticleDOI
Catalytic enantioselective alkyl and aryl addition to aldehydes and ketones with organozinc reagents derived from alkyl Grignard reagents or arylboronic acids
TL;DR: A highly practical, catalytic enantioselective alkyl and aryl addition to aldehydes and ketones with organozinc reagents, which were prepared in situ from commercially available Grignard reagents or aryalboronic acids.
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Vanadium‐Catalyzed Asymmetric Oxidation of Sulfides Using Schiff Base Ligands Derived from β‐Amino Alcohols with Two Stereogenic Centers
TL;DR: In this paper, a new Schiff base ligands derived from β-amino alcohols with two stereogenic centers were used in the preparation of optically pure sulfoxides by using aqueous hydrogen peroxide as the oxidant.
Journal ArticleDOI
Mannich and O‐Alkylation Reactions of Tetraalkoxyresorcin[4]arenes – The Use of Some Products in Ligand‐Assisted Reactions
Benjamin R. Buckley,Jonathan Y. Boxhall,Philip C. Bulman Page,Yohan Chan,Mark R. J. Elsegood,Harry Heaney,Kathryn E. Holmes,Matthew J. McIldowie,Vickie McKee,Matthew J. McGrath,Mauro Mocerino,Andrew M. Poulton,Edward P. Sampler,Brian W. Skelton,Allan H. White +14 more
TL;DR: In this paper, a series of Mannich bases derived from racemic tetraalkoxyresorcin[4]arenes was obtained under microwave-assisted aprotic reaction conditions and the use of preformed iminium ion intermediates.
Journal ArticleDOI
Catalytic asymmetric synthesis of chiral diol, bis[2-(1-hydroxyalkyl)-phenyl]ether, an asymmetric autocatalytic reaction
TL;DR: In this paper, Zinc alkoxides of chiral diols were found to work as asymmetric autocatalysts in the reaction between bis(2-formylphenyl)ether and dialkylzincs.
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