Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Enantioselective Conjugate Addition of Diethylzinc to Chalcone Catalyzed by Ni(acac)2 and Chiral β‐Amino Alcohols
TL;DR: In this paper, an asymmetric conjugate addition of diethylzinc to chalcone was carried out in the presence of Ni(acac)2 complexed with five pyrrolidinylmethanols derived from L-proline.
Journal ArticleDOI
Synthesis of new polydentate oxalamide-based ligands as chiral catalysts for the enantioselective addition of diethylzinc to benzaldehyde
TL;DR: New polydentate oxalamide-based ligands have been studied as chiral catalysts in the enantioselective addition of diethylzinc to benzaldehyde.
Journal ArticleDOI
Lanthanide complexes combined with chiral salen ligands: application in the enantioselective epoxidation reaction of α,β-unsaturated ketones
TL;DR: In this paper, the salen-La complex was used for enantioselective epoxidation of α,β-unsaturated ketones, and it was found that salen ligands showed the highest efficiency and enanti-lectivity.
Journal ArticleDOI
Exploration of ω-side chain addition strategies for the syntheses of isocarbacyclin and 15R-16-(m-tolyl)-17,18,19,20-tetranorisocarbacyclin
Neil A. Sheddan,Johann Mulzer +1 more
TL;DR: Alternative access to prostacyclin analogues is described by means of two omega-side chain addition strategies: Grignard reagent addition to an alpha,beta-unsaturated Weinreb amide, followed by diastereoselective reduction of the corresponding enone system, and implementation of Seebach's alkylation chemistry.
Journal ArticleDOI
Stereodivergent Synthesis of Camphor-Derived Diamines and Their Application as Thiourea Organocatalysts.
TL;DR: Diamines were transformed into the corresponding noncovalent bifunctional thiourea organocatalysts, which have been evaluated for catalytic activity in the conjugative addition of 1,3-dicarbonyl nucleophiles (dimethyl malonate, acetylacetone, and dibenzoylmethane) to trans-β-nitrostyrene.
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