Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Enantioselective alkynylation of aldehydes catalyzed by a camphor sulfonylated amino alcohols titanium(IV) catalyst system
TL;DR: In this paper, a new titanium(IV) complex was developed for the effective enantioselective alkynylation of phenylacetylene addition to aldehydes, which was readily prepared in situ from (R)-C-(7,7-dimethyl-2-oxo-bicyclo[2.2.1]hept-1-yl)-(1R,2S)-N-(2-hydroxy-1,2-diphenyl-ethyl)-methanesulfonamide (1h) and tet
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Synthesis of new Schiff base-camphorsulfonyl amide ligands and in situ screening in the asymmetric additions of organozinc reagents to aldehydes
TL;DR: In this paper, a new library of highly modular Schiff base-camphorsulfonyl amide ligands from readily available starting materials has been designed and synthesized for asymmetric addition of diethyl zinc to aldehydes in good yields and high enantioselectivities.
Journal ArticleDOI
Straightforward synthesis of [(2S,4R)-1-cyclohexyl-4-methylpiperidin-2-yl] methanol and [(2S,4R)-1-cyclohexyl-4-methylpiperidin-2-yl](diphenyl)methanol: Novel chiral ligands for the catalytic addition of diethylzinc to benzaldehyde to give rise to an extensive turn in the sense of asymmetric induction
TL;DR: In this article, the enantioselective addition of diethylzinc to benzaldehyde mediated by ligands 5a and 5c has been studied with DFT methods.
Reference EntryDOI
Additions of Allyl, Allenyl, and Propargylstannanes to Aldehydes and Imines
TL;DR: The most efficient tools for this strategy include modern aldol reactions and the reaction of carbonyl compounds with allyl metal reagents as discussed by the authors. But these tools are not suitable for the synthesis of polyacetate and polypropionate structures.
Journal ArticleDOI
Recent developments in Zn-catalyzed asymmetric addition reaction to ketones: Syntheses of chiral tertiary alcohols
TL;DR: In this paper, the recent developments of this asymmetric protocol are focused, and a review of the most recent developments can be found in Section 5.1.1] and Section 6.2.
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