Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Reference EntryDOI
Structural Organozinc Chemistry
TL;DR: In this article, a Zinc Transition Metal Bond (ZMTB) was proposed for organozinc compounds containing a zinc transition metal bond (ZMMB) containing a ZMTB and a diacl-and diarylzinc compound.
Journal ArticleDOI
Estrone derived 2-naphthol analogue in the diastereoselective one-pot Betti-condensation.
Irena Zagranyarska,Kalina Kostova,Yulian Zagranyarski,Rositsa P. Nikolova,Boris Shivachev,Vladimir Dimitrov +5 more
TL;DR: The utility of deoxy-isoequilenine synthesized from estrone as valuable 2-naphthol analogue is demonstrated in the three components Betti-condensation.
Journal ArticleDOI
New 1,3-amino alcohols derived from enantiopure bridgehead β-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acids
Christophe André,Monique Calmes,Françoise Escale,Muriel Amblard,Jean Martinez,Olivier Songis +5 more
TL;DR: Constrained enantiopure bicyclic β-amino acids derived from the asymmetric Diels–Alder reaction of the (R)-benzyl-4-(3-acryloyloxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)-benzoate and the 1-(benZyloxycarbonylamino)cyclohexadiene provide original templates for the construction of new rigid enantsiopure
Posted ContentDOI
From Desktop to Benchtop – A Paradigm Shift in Asymmetric Synthesis
Mihai Burai Patrascu,Joshua Pottel,Sharon Pinus,Michelle Bezanson,Per-Ola Norrby,Nicolas Moitessier +5 more
TL;DR: Virtual Chemist as mentioned in this paper is a platform for predicting outcomes of asymmetric chemical reactions ahead of testing in the lab, in just a few clicks, using simulation of various sets of experiments, including one-by-one design, library screening, hit optimization, and substrate scope evaluation.
Journal ArticleDOI
Mechanism Change of (+)-Nonlinear Effect in a Phase Separation System in a CuII-Catalyzed Asymmetric Friedel-Crafts Reaction Using a C2-Chiral Dioxolane-Containing-Bisamidine Ligand, Naph-diPIM-dioxo-iPr
TL;DR: A CuII complex of bisamidine ligand LS, chirally modified naphtho[1,2-b:7,8-b′]dipyrroloimidazole (Naph-diPIM), catalyzes the enantioselective Friedel-Crafts (FC) reaction of indole (1a) with ethyl as mentioned in this paper.
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