Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Catalytic asymmetric alkylation of aldehydes by diethylzinc in the presence of N-iso-propylephedrine; dependence of enantioselectzvity on Et2Zn:RCHO
TL;DR: In this article, the enantioselective alkylation of a range of aldehydes by diethylzinc in the presence of N-isopropylephedrine has been investigated.
Journal ArticleDOI
Chiral aminoalcohols with a menthane skeleton as catalysts for the enantioselective addition of diethylzinc to benzaldehyde
TL;DR: In this paper, a chiral amino alcohol was synthesized by highly diastereoselective addition of Me3SiCN and LiCH2CN to (−)-menthone followed by LiAlH4 reduction.
Journal ArticleDOI
Enantioselective dialkylzinc-mediated alkynylation, arylation and alkenylation of carbonyl groups
TL;DR: In this article, a comprehensive review of methods based on the use of readily available diethyl-and dimethylzinc for the formation of more complex compounds are compared and discussed.
Journal ArticleDOI
Catalytic Enantioselective Alkylation and Arylation of Aldehydes by Using Grignard Reagents
TL;DR: In this article, the authors developed an efficient and practical method for the catalytic enantioselective alkylation and arylation of aldehydes by using Grignard reagents in combination with titanium tetraisopropoxid.
Journal ArticleDOI
Catalytic Enantioselective Addition of MeMgBr and Other Grignard Reagents to Aldehydes
TL;DR: An efficient catalyst is reported for the challenging enantioselective addition of MeMgBr to aldehydes and a variety of Grignard reagents can be also added to aromatic and aliphatic aldeHydes in good yields and enantiOSElectivities in a simple one-pot procedure under mild conditions.
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