Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
Citations
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Journal ArticleDOI
Unexpected efficiency of non‐C2‐symmetric bis(hydroxyamide)‐based zinc‐chelate catalysts
Esther M. Sánchez-Carnerero,Tomás de las Casas Engel,Beatriz Lora Maroto,Santiago de la Moya Cerero +3 more
TL;DR: The previously established assumption on the necessity of using C(2) -symmetric bis(hydrdoxyamides) to generate C( 2) -Symmetric zinc-chelate catalysts can be discarded and the possibilities for designing new ligands based on the interesting hydroxyl-amide functional grouping are expanded.
Journal ArticleDOI
Synthesis of (R)-(−)-1-Piperidino-3,3-dimethylbutan-2-ol: Application in the Molar Scale Asymmetric Ethylation of trans-Crotonaldehyde
TL;DR: A simple three-step preparation of (R)-(−)-1-piperidino-3,3-dimethylbutan-2-ol (amino alcohol catalyst for the Noyori asymmetric alkylation of aldehydes) based on a classical resolution of the race is described in this article.
Journal ArticleDOI
Immobilization of chiral amide derived from (1R,2S)-(−)-norephedrine over 3D nanoporous silica for the enantioselective addition of diethylzinc to aldehydes
Umesh Balakrishnan,Umesh Balakrishnan,Nallamuthu Ananthi,Sivan Velmathi,Mercy R. Benzigar,Siddulu Naidu Talapaneni,Salem S. Al-Deyab,Katsuhiko Ariga,Ajayan Vinu,Ajayan Vinu +9 more
TL;DR: In this paper, a chiral amide synthesized from (1R, 2S)-(-)-norephedrine has been successfully immobilized onto three dimensional Ia3d cubic nanoporous material.
Patent
Catalysts for asymmetric addition of organozinc regents to aldehydes and method for preparation
TL;DR: In this article, the authors proposed a chiral amino alcohol catalysts for aliphatic aldehydes containing a β-branch with greatly enhanced enantioselectivity relative to DAIB.
Journal ArticleDOI
Design, synthesis, and application of novel chiral ONN ligands for asymmetric alkylation
TL;DR: In this article, a set of chiral ONN ligands were synthesized and their catalytic potential was examined in asymmetric alkylation, and they were successfully applied as catalysts in the addition of diethyl zinc to various aromatic aldehydes, yielding secondary alcohols in excellent yields of up to 99% ee.
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