Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Synthesis and reductions of (1R,4E,5S)-4-oximino-1,8,8-trimethyl-2-oxabicyclo[3.2.1]octan-3-one
TL;DR: In this article, the structure of octan-3-one derivatives were determined by X-ray diffraction and the results showed that (1R,4E,5S)-4-dialkylamino-1,8,8-trimethyl-2-oxabicyclo[3.2.1] can be reduced with Grignard reagents.
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Utilization of industrial waste materials. Part 14.† Synthesis of β-amino alcohols and thiols with a 2-azabicyclo[3.3.0]octane backbone and their application in enantioselective catalysis
Michael Kossenjans,Michael Soeberdt,Sabine Wallbaum,Klaus Harms,Jürgen Martens,Hans Günter Aurich +5 more
TL;DR: In this article, chiral β-tert-amino tert-alcohols were synthesized from the enantiomerically pure sec-amine (all-R)-1b via the new glycine, alanine and phenylglycine derivatives.
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Enantioselective addition of diethylzinc to aromatic aldehydes catalyzed by 14-hydroxylsubstituted morphinans
Minoo Dabiri,Peyman Salehi,Gholamreza Kozehgary,Seddigheh Heydari,Akbar Heydari,Maryam Esfandyari +5 more
TL;DR: In this paper, an enantioselective addition of diethylzinc to aromatic aldehydes was performed with catalytic amounts of 14-hydroxylsubstituted morphine alkaloids.
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Understanding the catalytic role of flexible chiral δ-amino alcohols: the 1-(2-aminoethyl)norbornan-2-ol model
Antonio García Martínez,Enrique Teso Vilar,Amelia García Fraile,Santiago de la Moya Cerero,Beatriz Lora Maroto +4 more
TL;DR: In this article, an empiric first approach to the knowledge about the structural factors influencing the catalytic behavior of conformationally flexible δ-amino-alcohol-based ligands, for the enantioselective addition of dialkylzincs to prochiral carbonyl groups, has been applied using the 1-(2aminoethyl)norbornan-2-ol moiety as the model chiral system, and the asymmetrically catalyzed addition of diethylzinc to benzaldehyde as the test reaction.
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Homo- vs. heterometallic organoaluminum fencholates: Structures and selectivities
TL;DR: In this paper, the O-BIFOL-based (Al, Li)-heterometallic fencholate (11) showed an increase and a change of the sense of enantioselectivity from 19% ee (S) to 62% Ee (R).
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