Journal ArticleDOI
Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes
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This article is published in Journal of the American Chemical Society.The article was published on 1986-09-01. It has received 479 citations till now. The article focuses on the topics: Addition reaction & Enantioselective synthesis.read more
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Chirale Ferrocenliganden in der asymmetrischen Katalyse
TL;DR: Ferrocenliganden wurden in zahlreichen enantioselektiven Prozessen unterschiedlichster Art eingesetzt, and dieser Aufsatz diskutiert die Fortschritte der letzten Jahre.
Journal ArticleDOI
Direct Vinylation of Alcohols or Aldehydes Employing Alkynes as Vinyl Donors: A Ruthenium Catalyzed C−C Bond-Forming Transfer Hydrogenation
TL;DR: Under the conditions of ruthenium catalyzed transfer hydrogenation, 2-butyne couples to benzylic and aliphatic alcohols 1a-1l to furnish allylic alcohols 2a-2l, constituting a direct C-H vinylation of alcohols employing alkynes as vinyl donors.
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Synthesis of N-Alkylated and N-Arylated Derivatives of 2-Amino-2‘-hydroxy-1,1‘-binaphthyl (NOBIN) and 2,2‘-Diamino-1,1‘-binaphthyl and Their Application in the Enantioselective Addition of Diethylzinc to Aromatic Aldehydes†
Štěpán Vyskočil,Stanislav Jaracz,Martin Smrčina,Martin Štícha,Vladimír Hanuš,and Miroslav Polášek,Pavel Kočovský +6 more
TL;DR: In this paper, high-yield reductive alkylation of (R)-(+)-1 and (R-(+))-2 has been achieved with a series of ketones (even as bulky as 2-adamantanone) and NaBH4/H2SO4 in THF at room temperature.
Journal ArticleDOI
Asymmetric catalysis: An enabling science
TL;DR: General themes for designing catalysts to effect asymmetric induction are helping to make this strategy more useful, in general, with the resultant effect of a marked enhancement of synthetic efficiency.
Journal ArticleDOI
Catalytic asymmetric synthesis of optically active alkynyl alcohols by enantioselective alkynylation of aldehydes and by enantioselective alkylation of alkynyl aldehydes
Seiji Niwa,Kenso Soai +1 more
TL;DR: In this article, an asymmetric synthesis of optically active secondary alkynyl alcohols by enantioselective addition of organozinc reagents to aldehydes in the presence of a small amount of catalyst was examined.
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