Cigarette smoking and telomere length: A systematic review of 84 studies and meta-analysis
TLDR
Shorter telomere length among ever smokers compared to those who never smoked may imply mechanisms linking tobacco smoke exposure to ageing‐related disease.About:
This article is published in Environmental Research.The article was published on 2017-10-01 and is currently open access. It has received 198 citations till now. The article focuses on the topics: Risk factor.read more
Citations
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Determinants of telomere length across human tissues
Kathryn Demanelis,Farzana Jasmine,Lin Chen,Meytal Chernoff,Lin Tong,Dayana A. Delgado,Chenan Zhang,Justin Shinkle,Mekala Sabarinathan,Hannah Lin,Eduardo Ramirez,Meritxell Oliva,Sarah Kim-Hellmuth,Sarah Kim-Hellmuth,Barbara E. Stranger,Barbara E. Stranger,Tsung Po Lai,Abraham Aviv,Kristin G. Ardlie,François Aguet,Habibul Ahsan,Jennifer A. Doherty,Muhammad G. Kibriya,Brandon L. Pierce +23 more
TL;DR: Evidence that RTL may mediate the effect of age on age on TL is found and sources of variation in TL are characterized to evaluate whole-blood TL as a proxy for TL in other tissue types, and examine the relationship between age and TL across tissue types.
Journal ArticleDOI
Sex and Gender Differences Research Design for Basic, Clinical, and Population Studies: Essentials for Investigators
Janet W. Rich-Edwards,Janet W. Rich-Edwards,Ursula B. Kaiser,Grace L Chen,JoAnn E. Manson,JoAnn E. Manson,Jill M. Goldstein +6 more
TL;DR: This work addresses issues of motivation, subject selection, sample size, data collection, analysis, and interpretation, and discusses why some inferences from sex-stratified data should be viewed with caution.
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The association between stressors and telomeres in non-human vertebrates: a meta-analysis.
TL;DR: Interestingly, the association between stressor exposure and telomeres in one hand, and oxidative stress in the other hand, covaried, suggesting the implication of oxidative Stress in telomere dynamics.
Journal ArticleDOI
Telomere Length as a Marker of Biological Age: State-of-the-Art, Open Issues, and Future Perspectives.
TL;DR: A review article as discussed by the authors describes the current state of the art in the field and discusses recent research findings and divergent viewpoints regarding the usefulness of leukocyte TL for estimating the human biological age.
Journal ArticleDOI
Telomeres and Telomere Length: A General Overview.
TL;DR: Telomeres hold potential as biomarkers that reflect the genetic predisposition together with the impact of environmental conditions and as targets for anti-cancer therapies.
References
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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