Journal ArticleDOI
Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target
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TLDR
Imaging of the brain and vessels has shown that collateral flow can sustain brain tissue for hours after the occlusion of major arteries to the brain, and the augmentation or maintenance of collateral flow is therefore a potential therapeutic target.Abstract:
Summary Ischaemic stroke results from acute arterial occlusion leading to focal hypoperfusion. Thrombolysis is the only proven treatment. Advanced neuroimaging techniques allow a detailed assessment of the cerebral circulation in patients with acute stroke, and provide information about the status of collateral vessels and collateral blood flow, which could attenuate the effects of arterial occlusion. Imaging of the brain and vessels has shown that collateral flow can sustain brain tissue for hours after the occlusion of major arteries to the brain, and the augmentation or maintenance of collateral flow is therefore a potential therapeutic target. Several interventions that might augment collateral blood flow are being investigated.read more
Citations
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Journal ArticleDOI
Relationship between estimated glomerular filtration rate and outcome of ischemic stroke patients after mechanical thrombectomy.
TL;DR: In this paper, the effect of preprocedural renal function on the outcome of acute ischemic stroke patients with mechanical thrombectomy (MT) and whether this effect is modified by the onset-to-reperfusion time (OTR) and mediated by collateral status was investigated.
Journal ArticleDOI
Mismatch of delayed perfusion volume between TTP and Tmax map of perfusion MRI.
TL;DR: The finding of a large TTP-Tmax perfusion delay mismatch volume in patients with acute stroke who have a PWI-DWI mismatch on an initial MRI may predict that the infarct volume will not increase despite persistent vascular occlusion.
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The significance of leptomeningeal collaterals in moyamoya disease
Jin Yu,Jibo Zhang,Jincao Chen +2 more
TL;DR: According to the authors, the wide range of complex LMC in the brain of MMD patients should lead to a variety of hemodynamic sources for parasylvian continental arteries (PSCAs) in MMD hemispheres, and results suggested that the recipient vessel in traditional “superficial temporal artery-middle cerebral artery (STA-MCA)” bypass surgery was not always from MCA.
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Pre-stroke Physical Activity and Cerebral Collateral Circulation in Ischemic Stroke: A Potential Therapeutic Relationship?
TL;DR: A hypothesis-generating discussion on the potential association between pre-stroke physical activity and cerebral collateral circulation in ischemic stroke is provided.
References
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Journal Article
Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology
Harold P. Adams,Gregory J. del Zoppo,Mark J. Alberts,Deepak L. Bhatt,Lawrence F. Brass,Anthony J. Furlan,Robert L. Grubb,Randall T. Higashida,Edward C. Jauch,Chelsea S. Kidwell,Patrick D. Lyden,Lewis B. Morgenstern,Adnan I Qureshi,Robert H. Rosenwasser,Phillip A. Scott,Eelco F. M. Wijdicks +15 more
TL;DR: The goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke.
Journal ArticleDOI
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
Harold P. Adams,Gregory J. del Zoppo,Mark J. Alberts,Deepak L. Bhatt,Lawrence M. Brass,Anthony J. Furlan,Robert L. Grubb,Randall T. Higashida,Edward C. Jauch,Chelsea S. Kidwell,Patrick D. Lyden,Lewis B. Morgenstern,Adnan I. Qureshi,Robert H. Rosenwasser,Phillip A. Scott,Eelco F.M. Wijdicks +15 more
TL;DR: In this paper, the authors provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke and provide information for healthcare policy makers.
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