Journal ArticleDOI
Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target
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TLDR
Imaging of the brain and vessels has shown that collateral flow can sustain brain tissue for hours after the occlusion of major arteries to the brain, and the augmentation or maintenance of collateral flow is therefore a potential therapeutic target.Abstract:
Summary Ischaemic stroke results from acute arterial occlusion leading to focal hypoperfusion. Thrombolysis is the only proven treatment. Advanced neuroimaging techniques allow a detailed assessment of the cerebral circulation in patients with acute stroke, and provide information about the status of collateral vessels and collateral blood flow, which could attenuate the effects of arterial occlusion. Imaging of the brain and vessels has shown that collateral flow can sustain brain tissue for hours after the occlusion of major arteries to the brain, and the augmentation or maintenance of collateral flow is therefore a potential therapeutic target. Several interventions that might augment collateral blood flow are being investigated.read more
Citations
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Journal ArticleDOI
A Staged Hybrid Procedure to Manage Complex Cerebral Hypoperfusion in Aortic Arch Aneurysm.
Teresa Hernández Carbonell,Stéphan Haulon,Alain Prat,Teresa Martin-Gonzalez,Mark R. Tyrrell,Jonathan Sobocinski +5 more
TL;DR: The management of a patient who had an open‐surgical repair following traumatic avulsion of the supra‐aortic trunks 30 years prior to presentation with a large arch aneurysm and poor cerebral collaterals is reported.
Journal ArticleDOI
Evaluation of Collateral Circulation in Patients with Acute Ischemic Stroke.
Keiko Fukuda,David S Liebeskind +1 more
TL;DR: The cerebral collateral circulation is an increasingly important consideration in the management of acute ischemic stroke and is a key determinant of outcomes as mentioned in this paper . But, more randomized trials are needed to evaluate the risks and benefits of endovascular reperfusion with consideration of collateral status.
Journal ArticleDOI
Can Computed Tomographic Angiography Be Used to Predict Who Will Not Benefit from Endovascular Treatment in Patients with Acute Ischemic Stroke? The CTA-ABC Score.
Hyo Sung Kwak,Jung-Soo Park +1 more
TL;DR: The authors' CTA-ABC score reliably assessed risk for sICH and/or MMCAI in patients with AIS who underwent EVT, and can support clinical decision-making, especially when the need for EVT is uncertain.
Journal ArticleDOI
Value of CT Perfusion for Collateral Status Assessment in Patients with Acute Ischemic Stroke
Haryadi Prasetya,Manon L. Tolhuisen,Miou S Koopman,Manon Kappelhof,Frederick J. A. Meijer,Lonneke S. F. Yo,Geert J. Lycklama á Nijeholt,Wim H. van Zwam,Aad Van Der Lugt,Yvo B.W.E.M. Roos,Charles B. L. M. Majoie,Ed van Bavel,Henk A. Marquering,On Behalf Of The Mr Clean Registry Investigators +13 more
TL;DR: In this article , the authors proposed a CTP-based collateral score, which is significantly associated with functional outcome and may serve as an alternative collateral measure in settings where MR imaging is not feasible.
Journal ArticleDOI
Association between symptomatic intracranial atherosclerotic disease and the integrity of the circle of Willis.
TL;DR: The severity of intracranial atherosclerosis was independently associated with the presence of posterior communicating arteries in patients with a complete anterior part of the circle of Willis.
References
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Journal Article
Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology
Harold P. Adams,Gregory J. del Zoppo,Mark J. Alberts,Deepak L. Bhatt,Lawrence F. Brass,Anthony J. Furlan,Robert L. Grubb,Randall T. Higashida,Edward C. Jauch,Chelsea S. Kidwell,Patrick D. Lyden,Lewis B. Morgenstern,Adnan I Qureshi,Robert H. Rosenwasser,Phillip A. Scott,Eelco F. M. Wijdicks +15 more
TL;DR: The goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke.
Journal ArticleDOI
Guidelines for the Early Management of Adults With Ischemic Stroke: A Guideline From the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists
Harold P. Adams,Gregory J. del Zoppo,Mark J. Alberts,Deepak L. Bhatt,Lawrence M. Brass,Anthony J. Furlan,Robert L. Grubb,Randall T. Higashida,Edward C. Jauch,Chelsea S. Kidwell,Patrick D. Lyden,Lewis B. Morgenstern,Adnan I. Qureshi,Robert H. Rosenwasser,Phillip A. Scott,Eelco F.M. Wijdicks +15 more
TL;DR: In this paper, the authors provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke and provide information for healthcare policy makers.
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