Detection sensitivity of influenza rapid diagnostic tests
Yuko Sakai-Tagawa,Makoto Ozawa,Shinya Yamada,Yuko Uchida,Takehiko Saito,Kazuo Takahashi,Norio Sugaya,Masato Tashiro,Yoshihiro Kawaoka +8 more
TLDR
The sensitivity of influenza rapid diagnostic tests currently available in Japan for various influenza virus strains, including human H7N9 and H5N1 isolates, were compared and it was found that all of the IRDTs examined detected these viruses; however, their detection sensitivities differed.Abstract:
The sensitivity of influenza rapid diagnostic tests (IRDTs) currently available in Japan for various influenza virus strains, including human H7N9 and H5N1 isolates, were compared and it was found that all of the IRDTs examined detected these viruses; however, their detection sensitivities differed.read more
Citations
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An integrated self-driven microfluidic device for rapid detection of the influenza A (H1N1) virus by reverse transcription loop-mediated isothermal amplification
TL;DR: In this paper, a self-driven microfluidic device was developed to rapidly detect the H1N1 influenza virus via a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay.
Journal ArticleDOI
A structure-free digital microfluidic platform for detection of influenza a virus by using magnetic beads and electromagnetic forces
TL;DR: This is the first time that a digital microfluidic platform was demonstrated such that the entire diagnostic process for influenza A H1N1 viruses could be performed by using electromagnetic forces, which could be promising for rapid and accurate diagnosis of influenza.
Journal ArticleDOI
Reactivity and sensitivity of commercially available influenza rapid diagnostic tests in Japan.
Yuko Sakai-Tagawa,Seiya Yamayoshi,Chiharu Kawakami,Mai Q. Le,Yuko Uchida,Takehiko Saito,Chairul A. Nidom,Ira Humaira,Kathy Toohey-Kurth,Abdel-Satar Arafa,Ming-Tsan Liu,Yuelong Shu,Yoshihiro Kawaoka +12 more
TL;DR: The reactivity and sensitivity of 25 IRDTs available in Japan for the detection of seasonal H1N1pdm09, H3N2, and type B viruses, as well as highly pathogenic H5 and H7 viruses are examined.
Journal ArticleDOI
Effectiveness of inactivated influenza vaccine in children by vaccine dose, 2013–18
Masayoshi Shinjoh,Norio Sugaya,Munehiro Furuichi,Eriko Araki,Naonori Maeda,Kyohei Isshiki,Takuma Ohnishi,Shoko Nakamura,Go Yamada,Atsushi Narabayashi,Mitsuhiro Nishida,Nobuhiko Taguchi,Yuji Nakata,Makoto Yoshida,Kenichiro Tsunematsu,Meiwa Shibata,Takeshi Munenaga,Yasuhiro Hirano,Ichiro Ookawara,Shinichiro Sekiguchi,Yasuaki Kobayashi,Yoshio Yamaguchi,Naoko Yoshida,Keiko Mitamura,Takao Takahashi +24 more
TL;DR: Both one- and two-doses regimens of IIV were effective in preventing influenza for children aged 6 months to 12 years and the two-dose regimen was more effective against influenza B in some seasons.
Journal ArticleDOI
Clinical evaluation of rapid fluorescent diagnostic immunochromatographic test for influenza A virus (H1N1).
Seung-Taek Yu,Cuc Thi Bui,Do Thi Hoang Kim,Anh Viet Thi Nguyen,Thuy Tien Thi Trinh,Seon-Ju Yeo +5 more
TL;DR: A rapid fluorescent immunochromatographic strip test that has the potential to improve the quality of current rapid POCT for the diagnosis of influenza A/H1N1 infection and had better sensitivity than RDT.
References
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MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
TL;DR: An advanced version of the Molecular Evolutionary Genetics Analysis software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis, is released, which enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny.
Brief Communication MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0
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Rongbao Gao,Bin Cao,Yunwen Hu,Zijian Feng,Dayan Wang,Wanfu Hu,Jian Chen,Zhijun Jie,Haibo Qiu,Ke Xu,Xuewei Xu,Hongzhou Lu,Wenfei Zhu,Zhancheng Gao,Nijuan Xiang,Yinzhong Shen,Zebao He,Y. Gu,Zhiyong Zhang,Yi Yang,Xiang Zhao,Lei Zhou,Xiaodan Li,Shumei Zou,Ye Zhang,Xiyan Li,Lei Yang,Junfeng Guo,Jie Dong,Qun Li,Libo Dong,Yun Zhu,Tian Bai,Shiwen Wang,Pei Hao,Weizhong Yang,Yanping Zhang,Jun Han,Hongjie Yu,Dexin Li,George F. Gao,Guizhen Wu,Yu Wang,Zhenghong Yuan,Yuelong Shu +44 more
TL;DR: Novel reassortant H7N9 viruses were associated with severe and fatal respiratory disease in three patients, and all three patients died.
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Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity.
C U Kim,W. Lew,M.A. Williams,Hua-Kun Liu,Lijun Zhang,S Swaminathan,N Bischofberger,Min Chen,D. B. Mendel,C. Y. Tai,W. G. Laver,Raymond C. Stevens +11 more
TL;DR: The design, synthesis, and in vitro evaluation of the novel carbocycles as transition-state-based inhibitors of influenza neuraminidase (NA) are described and the presence of a large hydrophobic pocket in the region corresponding to the glycerol subsite of sialic acid is revealed.
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Oseltamivir Resistance during Treatment of Influenza A (H5N1) Infection
de Jong,Tran Tt,Truong Hk,Vo Mh,Gavin J. D. Smith,Nguyen Vc,Bach Vc,Phan Tq,Do Qh,Yi Guan,Joseph Malik Sriyal Peiris,Tran Th,Jeremy Farrar +12 more
TL;DR: It is suggested that resistance can emerge during the currently recommended regimen of oseltamivir therapy and may be associated with clinical deterioration and that the strategy for the treatment of influenza A (H5N1) virus infection should include additional antiviral agents.