Dietary phytochemicals modulate intestinal epithelial barrier dysfunction and autoimmune diseases
Kumar Ganesan,Kumar Ganesan,José L. Quiles,Maria Daglia,Maria Daglia,Jianbo Xiao,Baojun Xu +6 more
- Vol. 2, Iss: 3, pp 357-382
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The article was published on 2021-09-01 and is currently open access. It has received 29 citations till now.read more
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Effects and mechanisms of dietary bioactive compounds on breast cancer prevention
TL;DR: In this article , a review focused on various dietary bioactive compounds as potential therapeutic agents in the prevention and treatment of breast cancer with the mechanisms of action, and the data of chemopreventive and anticancer activity of dietary bio-active compounds were collected and orchestrated in a suitable place in the review.
Recent advance of in vitro models in natural phytochemicals absorption and metabolism
TL;DR: In this paper , the authors introduce the advantages and disadvantages of commonly used in vitro simulation models of natural phytochemicals absorption and metabolism, as well as briefly introduces the working principle of each model.
Journal ArticleDOI
Effects and mechanisms of dietary bioactive compounds on breast cancer prevention.
TL;DR: In this article, a review focused on various dietary bioactive compounds as potential therapeutic agents in the prevention and treatment of breast cancer with the mechanisms of action, and the data of chemopreventive and anticancer activity of dietary bio-active compounds were collected and orchestrated in a suitable place in the review.
Journal ArticleDOI
Rhodomyrtus tomentosa (Ait.) Hassk fruit phenolic-rich extract mitigates intestinal barrier dysfunction and inflammation in mice.
TL;DR: In this article , the mitigative effect of Rhodomyrtus tomentosa (Ait.) Hassk fruit extract rich in phenolic compounds (RTE) on high fat diet (HFD)-induced intestinal barrier dysfunction of mice and the underlying mechanism were explored.
Journal ArticleDOI
Dietary proanthocyanidins on gastrointestinal health and the interactions with gut microbiota.
TL;DR: The potential effects of PAC in prevention and alleviation of gastrointestinal diseases are remarkable but clinical evidence is urgently needed.
References
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A human gut microbial gene catalogue established by metagenomic sequencing
Junjie Qin,Ruiqiang Li,Jeroen Raes,Manimozhiyan Arumugam,Kristoffer Sølvsten Burgdorf,Chaysavanh Manichanh,Trine Nielsen,Nicolas Pons,Florence Levenez,Takuji Yamada,Daniel R. Mende,Junhua Li,Junming Xu,Shaochuan Li,Dongfang Li,Jianjun Cao,Bo Wang,Huiqing Liang,Huisong Zheng,Yinlong Xie,Julien Tap,Patricia Lepage,Marcelo Bertalan,Jean-Michel Batto,Torben Hansen,Denis Le Paslier,Allan Linneberg,H. Bjørn Nielsen,Eric Pelletier,Pierre Renault,Thomas Sicheritz-Pontén,Keith Turner,Hongmei Zhu,Chang Yu,Shengting Li,Min Jian,Yan Zhou,Yingrui Li,Xiuqing Zhang,Songgang Li,Nan Qin,Huanming Yang,Jian Wang,Søren Brunak,Joël Doré,Francisco Guarner,Karsten Kristiansen,Oluf Pedersen,Julian Parkhill,Jean Weissenbach,Peer Bork,S. Dusko Ehrlich,Jun Wang +52 more
TL;DR: The Illumina-based metagenomic sequencing, assembly and characterization of 3.3 million non-redundant microbial genes, derived from 576.7 gigabases of sequence, from faecal samples of 124 European individuals are described, indicating that the entire cohort harbours between 1,000 and 1,150 prevalent bacterial species and each individual at least 160 such species.
Journal ArticleDOI
Enterotypes of the human gut microbiome
Manimozhiyan Arumugam,Jeroen Raes,Eric Pelletier,Denis Le Paslier,Takuji Yamada,Daniel R. Mende,Gabriel Fernandes,Julien Tap,Thomas Brüls,Jean-Michel Batto,Marcelo Bertalan,Natalia Borruel,Francesc Casellas,Leyden Fernández,Laurent Gautier,Torben Hansen,Masahira Hattori,Tetsuya Hayashi,Michiel Kleerebezem,Ken Kurokawa,Marion Leclerc,Florence Levenez,Chaysavanh Manichanh,H. Bjørn Nielsen,Trine Nielsen,Nicolas Pons,Julie Poulain,Junjie Qin,Thomas Sicheritz-Pontén,Sebastian Tims,David Torrents,Edgardo Ugarte,Erwin G. Zoetendal,Jun Wang,Francisco Guarner,Oluf Pedersen,Willem M. de Vos,Søren Brunak,Joël Doré,Jean Weissenbach,S. Dusko Ehrlich,Peer Bork +41 more
TL;DR: Three robust clusters (referred to as enterotypes hereafter) are identified that are not nation or continent specific and confirmed in two published, larger cohorts, indicating that intestinal microbiota variation is generally stratified, not continuous.
Journal ArticleDOI
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
Carlotta De Filippo,Duccio Cavalieri,Monica Di Paola,Matteo Ramazzotti,Jean Baptiste Poullet,Sébastien Massart,Silvia Collini,Giuseppe Pieraccini,Paolo Lionetti +8 more
TL;DR: In this paper, the authors compared the fecal microbiota of European children (EU) and that of children from a rural African village of Burkina Faso (BF), where the diet, high in fiber content, is similar to that of early human settlements at the time of the birth of agriculture.
Journal ArticleDOI
Diversity, stability and resilience of the human gut microbiota
Catherine A. Lozupone,Jesse Stombaugh,Jeffrey I. Gordon,Janet K. Jansson,Rob Knight,Rob Knight +5 more
TL;DR: Viewing the microbiota from an ecological perspective could provide insight into how to promote health by targeting this microbial community in clinical treatments.
The impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and Rural Africa
Duccio Cavalieri,M. Di Paola,Matteo Ramazzotti,J.B. Poullet,Sébastien Massart,Giuseppe Pieraccini,Paolo Lionetti,C. De Filippo +7 more
TL;DR: It is hypothesized that gut microbiota coevolved with the polysaccharide-rich diet of BF individuals, allowing them to maximize energy intake from fibers while also protecting them from inflammations and noninfectious colonic diseases.