Journal ArticleDOI
Evidence for transposition of dispersed repetitive DNA families in yeast
TLDR
In this paper, Dispersed repetitive DNA sequences from yeast (Saccharomyces cerevisiae) nuclear DNA have been isolated as molecular hybrids in lambdagt and showed marked alterations in the size of the restriction fragments containing these repetitive DNAs.About:
This article is published in Cell.The article was published on 1979-04-01. It has received 446 citations till now. The article focuses on the topics: Repeated sequence & Restriction fragment.read more
Citations
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Journal ArticleDOI
Gain of new exons and promoters by lineage-specific transposable elements-integration and conservation event on CHRM3 gene.
Jae-Won Huh,Young-Hyun Kim,Sang-Rae Lee,Hyoungwoo Kim,Dae-Soo Kim,Heui-Soo Kim,Han-Seok Kang,Kyu-Tae Chang +7 more
TL;DR: Taken together, exon-acquisition and alternative splicing events of CHRM3 genes were shown to have occurred through the continuous integration of transposable elements following conservation.
Journal ArticleDOI
The biochemical and genetic discovery of the SAGA complex.
TL;DR: In this article, the early genetic and biochemical experiments that led to the discovery of SAGA and the elucidation of its multiple activities are reviewed.
Journal ArticleDOI
Isolation of a DNA fragment that is expressed as an amber suppressor when present in high copy number in yeast
TL;DR: A plasmid carrying a DNA sequence conferring amber suppression has been isolated from yeast pool 35 DNA and the suppressor sequence was shown to integrate close to the MAL4 gene located on the right arm of chromosome XI.
Book ChapterDOI
Genetics of resistance to virus-induced leukemias.
Daniel Meruelo,Richard G. Bach +1 more
TL;DR: The chapter highlights the virology of leukemia-inducing and related viruses, discusses the issues of specificity in virus-host genomic interaction, and describes the current knowledge of host genes conferring resistance or susceptibility to virus-induced neoplasia.
Journal ArticleDOI
Fate of donor insertion sequence IS1 during transposition.
TL;DR: Results suggest that a copy of a donor ISI is inserted at the new site, and a model for transposition is prevented that postulates that a reactive intermediate is formed by a tandem duplication of a transposable sequence.
References
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Journal ArticleDOI
Detection of specific sequences among DNA fragments separated by gel electrophoresis.
TL;DR: This paper describes a method of transferring fragments of DNA from agarose gels to cellulose nitrate filters that can be hybridized to radioactive RNA and hybrids detected by radioautography or fluorography.
Journal ArticleDOI
Screening lambdagt recombinant clones by hybridization to single plaques in situ
WD Benton,Ronald W. Davis +1 more
TL;DR: A rapid, direct method for screening single plaques of Agt recombinant phage is described, which allows at least 10(6) clones to be screened per day and simplifies physical containment of recombinants.
Book ChapterDOI
[31] Electron microscope heteroduplex methods for mapping regions of base sequence homology in nucleic acids
Journal ArticleDOI
Analysis of restriction fragments of T7 DNA and determination of molecular weights by electrophoresis in neutral and alkaline gels.
TL;DR: Electrophoresis in alkaline gels can provide accurate molecular weights for linear, single-Stranded DNAs, and should be useful in analyzing DNA for single-strand breaks, depurinations or topological differences such as ring forms.
Journal ArticleDOI
Chromosome organization and genic expression.
TL;DR: Presented at the Cold Spring Harbor Symposium in 1951, this paper focused on regulation and development rather than transposition, and strongly reflected McClintock's newfound interest in theory.