Journal ArticleDOI
Executive dysfunction in Parkinson's disease: a review.
TLDR
This review discusses how executive deficits relate to pathology in specific territories of the basal ganglia, consider the impact of dopaminergic treatment on executive function (EF) in this context, and review the changes in EFs with disease progression.Abstract:
Executive dysfunction can be present from the early stages of Parkinson's disease (PD). It is characterized by deficits in internal control of attention, set shifting, planning, inhibitory control, dual task performance, and on a range of decision-making and social cognition tasks. Treatment with dopaminergic medication has variable effects on executive deficits, improving some, leaving some unchanged, and worsening others. In this review, we start by defining the specific nature of executive dysfunction in PD and describe suitable neuropsychological tests. We then discuss how executive deficits relate to pathology in specific territories of the basal ganglia, consider the impact of dopaminergic treatment on executive function (EF) in this context, and review the changes in EFs with disease progression. In later sections, we summarize correlates of executive dysfunction in PD with motor performance (e.g., postural instability, freezing of gait) and a variety of psychiatric (e.g., depression, apathy) and other clinical symptoms, and finally discuss the implications of these for the patients' daily life.read more
Citations
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Journal ArticleDOI
Low to moderate relationships between gait and postural responses in Parkinson disease.
TL;DR: Low to moderate relationships between gait and postural responses indicate the complexity of postural control and the potential involvement of different neural circuitry across these tasks in people with Parkinson's disease with and without freezing of gait.
Journal ArticleDOI
Verb naming fluency in hypokinetic and hyperkinetic movement disorders
TL;DR: The results showed that all participants performed similarly in all of the fluency tasks, and mean action content of the verbs produced in action fluency did not differ between groups.
Journal ArticleDOI
How to Assess Executive Functions in a Low-Educated and Multicultural Population Using a Switching Verbal Fluency Test (the TFA-93) in Neurodegenerative Diseases?
Pauline Narme,Didier Maillet,Didier Maillet,Juliette Palisson,Hervé Le Clésiau,Christine Moroni,Catherine Belin,Catherine Belin +7 more
TL;DR: In low-educated and multicultural populations, the TFA-93 seems to be a good alternative to assess flexibility compared to the standard neuropsychological tools based on academic abilities.
Book
Language in Dementia
TL;DR: In this article, a comprehensive examination of language and communication in individuals with cognitive impairment and dementia is presented, where each chapter covers a specific neurodegenerative disorder, and addresses the epidemiology, aetiology, pathophysiology, prognosis and clinical features, along with the assessment and treatment of these disorders by speech-language pathologists.
Journal ArticleDOI
Emotional Processing Impairments in Apathetic Patients with Parkinson's Disease: An ERP Study in Early Time Windows.
TL;DR: The findings suggested that emotional processing was impaired in apathetic PD patients and that the right hemisphere was more sensitive to reflecting this impairment in the early time windows of ERPs.
References
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