Journal ArticleDOI
Flexible and Highly Biocompatible Nanofiber-Based Electrodes for Neural Surface Interfacing.
Dong Nyoung Heo,Han-Jun Kim,Yi Jae Lee,Min Heo,Sang Jin Lee,Donghyun Lee,Sun Hee Do,Soo Hyun Lee,Il Keun Kwon +8 more
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TLDR
An NF-based nerve electrode that can be simply fabricated and easily applied due to its high permeability, flexibility, and biocompatibility is demonstrated and can record stable neural signals for extended periods of time.Abstract:
Polyimide (PI)-based electrodes have been widely used as flexible biosensors in implantable device applications for recording biological signals. However, the long-term quality of neural signals obtained from PI-based nerve electrodes tends to decrease due to nerve damage by neural tissue compression, mechanical mismatch, and insufficient fluid exchange between the neural tissue and electrodes. Here, we resolve these problems with a developed PI nanofiber (NF)-based nerve electrode for stable neural signal recording, which can be fabricated via electrospinning and inkjet printing. We demonstrate an NF-based nerve electrode that can be simply fabricated and easily applied due to its high permeability, flexibility, and biocompatibility. Furthermore, the electrode can record stable neural signals for extended periods of time, resulting in decreased mechanical mismatch, neural compression, and contact area. NF-based electrodes with highly flexible and body-fluid-permeable properties could enable future neural...read more
Citations
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Journal ArticleDOI
Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording
Yingchao Zhang,Ning Zheng,Yu Cao,Fengle Wang,Peng Wang,Yinji Ma,Bingwei Lu,Guohui Hou,Zizheng Fang,Ziwei Liang,Mengkun Yue,Yan Li,Ying Chen,Fu Ji,Jian Wu,Tao Xie,Xue Feng +16 more
TL;DR: A 3D twining electrode is proposed by integrating stretchable mesh serpentine wires onto a flexible shape memory substrate, which has permanent shape reconfigurability, distinct elastic modulus controllability, and shape memory recoverability at body temperature.
Journal ArticleDOI
Flexible Breathable Nanomesh Electronic Devices for On-Demand Therapy
Journal ArticleDOI
Biocompatibility of Polyimides: A Mini-Review
TL;DR: Various PIs have the capacity to accommodate in vivo conditions in which they are able to function for a long time and can be judiciously certified as biocompatible.
Journal ArticleDOI
Multifunctional Glycerol-Water Hydrogel for Biomimetic Human Skin with Resistance Memory Function.
TL;DR: The as-prepared GW hydrogel exhibits a fast self-healing efficiency and good adhesiveness against diverse substrates under a wide range of temperatures, and possesses good perceived ability for external stimuli and subtle/large human motions, which make it potentially significant in mimicking the human skin in real world.
Journal ArticleDOI
Toward Self-Control Systems for Neurogenic Underactive Bladder: A Triboelectric Nanogenerator Sensor Integrated with a Bistable Micro-Actuator.
Faezeh Arab Hassani,Roshini Priya Mogan,Gil Gerald Lasam Gammad,Hao Wang,Shih-Cheng Yen,Nitish V. Thakor,Chengkuo Lee +6 more
TL;DR: A bistable actuator to empty the bladder by incorporating shape memory alloy components integrated on flexible polyvinyl chloride sheets and integrates a flexible triboelectric nanogenerator sensor with the actuator with the capability for defining a self-control system in the future that would allow autonomous micturition.
References
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Journal ArticleDOI
Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application: An updated report from an I.F.C.N. Committee
Paolo Maria Rossini,David Burke,Robert Chen,L.G. Cohen,Zafiris J. Daskalakis,R. Di Iorio,V. Di Lazzaro,Florinda Ferreri,Florinda Ferreri,Paul B. Fitzgerald,Mark S. George,Mark Hallett,Jean-Pascal Lefaucheur,Berthold Langguth,Hideyuki Matsumoto,Carlo Miniussi,Michael A. Nitsche,Alvaro Pascual-Leone,Walter Paulus,Simone Rossi,John C. Rothwell,Hartwig R. Siebner,Yoshikazu Ugawa,Vincent Walsh,Ulf Ziemann +24 more
TL;DR: These guidelines provide an up-date of previous IFCN report on “Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application” and include some recent extensions and developments.
Journal ArticleDOI
Neural stimulation and recording electrodes.
TL;DR: Techniques for characterizing electrochemical properties relevant to stimulation and recording are described with examples of differences in the in vitro and in vivo response of electrodes.
Journal ArticleDOI
Electrospinning of polymeric nanofibers for drug delivery applications
TL;DR: The inherently high surface to volume ratio of electrospun fibers can enhance cell attachment, drug loading, and mass transfer properties of these fibers.
Journal ArticleDOI
Conducting‐Polymer Nanotubes for Controlled Drug Release
TL;DR: A method to prepare conducting-polymer nanotubes that can be used for precisely controlled drug release and significantly decrease the impedance and increase the charge capacity of the recording electrode sites on microfabricated neural prosthetic devices is reported on.
Journal ArticleDOI
Electronic dura mater for long-term multimodal neural interfaces
Ivan R. Minev,Pavel Musienko,Arthur Hirsch,Quentin Barraud,Nikolaus Wenger,Eduardo Martin Moraud,Jerome Gandar,Marco Capogrosso,Tomislav Milekovic,Leonie Asboth,Rafael Fajardo Torres,Nicolas Vachicouras,Nicolas Vachicouras,Qihan Liu,N. V. Pavlova,Simone Duis,Alexandre Larmagnac,Janos Vörös,Silvestro Micera,Silvestro Micera,Zhigang Suo,Grégoire Courtine,Stéphanie P. Lacour +22 more
TL;DR: In this paper, the shape and elasticity of dura mater, the protective membrane of the brain and spinal cord, was designed and fabricated for implantable neuroprostheses, which embeds interconnects, electrodes and chemotrodes that sustain millions of mechanical stretch cycles, electrical stimulation pulses, and chemical injections.
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Electronic dura mater for long-term multimodal neural interfaces
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