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Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma (2019 Edition).

Jian Zhou, +77 more
- 11 Nov 2020 - 
- Vol. 9, Iss: 6, pp 682-720
TLDR
The new guidelines were endorsed and promulgated by the Bureau of Medical Administration of the National Health Commission of the People’s Republic of China in December 2019 and reflect the real-world situation in China regarding diagnosing and treating liver cancer in recent years.
Abstract
Background: Primary liver cancer, around 90% are hepatocellular carcinoma in China, is the fourth most common malignancy and the second leading cause of tumor-related death, thereby posing a significant threat to the life and health of the Chinese people. Summary: Since the publication of Guidelines for Diagnosis and Treatment of Primary Liver Cancer (2017 Edition) in 2018, additional high-quality evidence has emerged with relevance to the diagnosis, staging, and treatment of liver cancer in and outside China that requires the guidelines to be updated. The new edition (2019 Edition) was written by more than 70 experts in the field of liver cancer in China. They reflect the real-world situation in China regarding diagnosing and treating liver cancer in recent years. Key Messages: Most importantly, the new guidelines were endorsed and promulgated by the Bureau of Medical Administration of the National Health Commission of the People’s Republic of China in December 2019.

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Immunotherapies for hepatocellular carcinoma.

TL;DR: A review of the immune microenvironments underlying the response or resistance of hepatocellular carcinoma (HCC) to immunotherapies is presented in this paper, where current evidence from phase III trials on the efficacy, immune-related adverse events and aetiology-dependent mechanisms of response are described.
Journal ArticleDOI

Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resectional surgery for hepatic tumors

TL;DR: Vol-CT can accurately assess the extent of liver resection, individuals with normal liver function can undergo resection of up to 60% of the nontumorous parenchyma without the need for PE, and PE can be used to reduce the size of the resected tissue and increase the volume of the remnant liver to approximate the target limits in individuals with large tumors or minimally abnormal liver function.
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Tumors of the Liver and Intrahepatic Bile Ducts

William A. Blanc
- 01 Dec 1958 - 
TL;DR: This new fascicle of the Atlas of Tumor Pathology is of the same high quality as most of the previous fascicles of the series, and combines, in a perfect balance, a profusion of excellent photographs and a well-written, sharp text.
Journal ArticleDOI

Hepatic Arterial Infusion of Oxaliplatin, Fluorouracil, and Leucovorin Versus Transarterial Chemoembolization for Large Hepatocellular Carcinoma: A Randomized Phase III Trial

TL;DR: In this article , the authors compared the overall survival of patients treated with FOLFOX-HAIC versus TACE as first-line treatment in large unresectable hepatocellular carcinoma.
References
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Journal ArticleDOI

Global cancer statistics

TL;DR: A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination, and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake.
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Global cancer statistics, 2012

TL;DR: A substantial portion of cancer cases and deaths could be prevented by broadly applying effective prevention measures, such as tobacco control, vaccination, and the use of early detection tests.
Journal ArticleDOI

EASL-EORTC clinical practice guidelines : management of hepatocellular carcinoma

TL;DR: The following Clinical Practice Guidelines will give up-to-date advice for the clinical management of patients with hepatocellular carcinoma, as well as providing an in-depth review of all the relevant data leading to the conclusions herein.
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