Journal ArticleDOI
Human milk: a source of more life than we imagine
Prescilla V. Jeurink,J. van Bergenhenegouwen,E. Jiménez,Léon M.J. Knippels,Leónides Fernández,Johan Garssen,Jan Knol,Juan M. Rodríguez,Rosario Martín +8 more
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TLDR
A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and lactation.Abstract:
The presence of bacteria in human milk has been acknowledged since the seventies. For a long time, microbiological analysis of human milk was only performed in case of infections and therefore the presence of non-pathogenic bacteria was yet unknown. During the last decades, the use of more sophisticated culture-dependent and -independent techniques, and the steady development of the -omic approaches are opening up the new concept of the ‘milk microbiome’, a complex ecosystem with a greater diversity than previously anticipated. In this review, possible mechanisms by which bacteria can reach the mammary gland (contamination versus active migration) are discussed. In addition, the potential roles of human milk for both infant and maternal health are summarised. A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and ...read more
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The microbiota of the respiratory tract: gatekeeper to respiratory health
Wing Ho Man,Wouter A. A. de Steenhuijsen Piters,Wouter A. A. de Steenhuijsen Piters,Debby Bogaert,Debby Bogaert +4 more
TL;DR: The epidemiological, biological and functional evidence that support the physiological role of the respiratory microbiota in the maintenance of human health are discussed.
Journal ArticleDOI
The infant microbiome development: mom matters
Noel T. Mueller,Elizabeth Bakacs,Joan Combellick,Zoya Grigoryan,Maria Gloria Dominguez-Bello +4 more
TL;DR: Recent knowledge about the impacts on infant microbiome assembly is reviewed, preventive and restorative strategies to ameliorate the effects of these impacts are discussed, and where research is needed to advance this field and improve the health of future generations are highlighted.
Journal ArticleDOI
Next-generation beneficial microbes : The case of Akkermansia muciniphila
TL;DR: It is proposed that microbes and microbiomegnosy, or knowledge of the authors' gut microbiome, can become a novel source of future therapies as plants and its related knowledge have been the source for designing drugs over the last century.
Journal ArticleDOI
Microbial Changes during Pregnancy, Birth, and Infancy.
TL;DR: The main factors shaping the infant microbiome—modes of delivery, feeding, weaning, and exposure to antibiotics are reviewed, starting to build a broader understanding of healthy vs. abnormal microbial alterations throughout major developmental time-points.
Journal ArticleDOI
Development of the gut microbiota in infancy and its impact on health in later life.
Masaru Tanaka,Jiro Nakayama +1 more
TL;DR: Recent findings regarding gut microbiota establishment are summarized, including the importance of various factors related to the development of the immune system and allergic diseases later in life are summarized.
References
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Journal ArticleDOI
Progesterone inhibits mature rat dendritic cells in a receptor-mediated fashion.
Cherie L. Butts,Shetha Shukair,Kristina M. Duncan,Eve Bowers,Cash Horn,Elena Belyavskaya,Leonardo H. Tonelli,Esther M. Sternberg +7 more
TL;DR: Data indicate that progesterone directly inhibits mature rat BMDC capacity to drive pro-inflammatory responses, which could contribute to or account for some of the differential expression of autoimmune/inflammatory disease in females.
Journal ArticleDOI
Comparative analysis of Salivary bacterial microbiome diversity in Edentulous infants and their mothers or primary care givers using pyrosequencing
Kimberly D. Cephas,Juhee Kim,Rose Ann Mathai,Kathleen A. Barry,Scot E. Dowd,Brandon Meline,Kelly S. Swanson +6 more
TL;DR: It is demonstrated that although the adult saliva bacterial microbiome had a greater OTU count than infants, a rich bacterial community exists in the infant oral cavity prior to tooth eruption.
Journal ArticleDOI
Nisin-Producing Lactococcus lactis Strains Isolated from Human Milk
Shea Beasley,Per E. J. Saris +1 more
TL;DR: Characterization by partial 16S rRNA gene sequencing, ribotyping, and green fluorescent protein-based nisin bioassay revealed that 6 of 20 human milk samples contained nisin-producing Lactococcus lactis bacteria, suggesting that the history of humans consuming nisin is older than the tradition of consuming fermented milk products.
Journal ArticleDOI
Staphylococcus epidermidis: a differential trait of the fecal microbiota of breast-fed infants.
Esther Jiménez,Susana Delgado,Antonio Maldonado,Rebeca Arroyo,Mar Albújar,Natalia García,Manel Jariod,Leónides Fernández,Adolfo Gómez,Juan M. Rodríguez +9 more
TL;DR: The presence of S. epidermidis is a differential trait of the fecal microbiota of breast-fed infants, which contains a low number of virulence determinants and are sensitive to most of the antibiotics tested.
Session 7: Prebiotics and probiotics usefulness against pathologies Potential role of the intestinal microbiota of the mother in neonatal immune education*
Anne Donnet-Hughes,Pablo Perez,Joël Doré,Marion Leclerc,Florence Levenez,Jalil Benyacoub,Patrick Serrant,Iris Segura-Roggero,Eduardo Schiffrin +8 more
TL;DR: In this paper, the authors show that human peripheral blood mononuclear cells and breast milk cells contain bacteria and their genetic material during lactation and that bacterial translocation is a unique physiological event, which is increased during pregnancy and lactation.