Journal ArticleDOI
Human milk: a source of more life than we imagine
Prescilla V. Jeurink,J. van Bergenhenegouwen,E. Jiménez,Léon M.J. Knippels,Leónides Fernández,Johan Garssen,Jan Knol,Juan M. Rodríguez,Rosario Martín +8 more
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TLDR
A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and lactation.Abstract:
The presence of bacteria in human milk has been acknowledged since the seventies. For a long time, microbiological analysis of human milk was only performed in case of infections and therefore the presence of non-pathogenic bacteria was yet unknown. During the last decades, the use of more sophisticated culture-dependent and -independent techniques, and the steady development of the -omic approaches are opening up the new concept of the ‘milk microbiome’, a complex ecosystem with a greater diversity than previously anticipated. In this review, possible mechanisms by which bacteria can reach the mammary gland (contamination versus active migration) are discussed. In addition, the potential roles of human milk for both infant and maternal health are summarised. A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and ...read more
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Relationships between the genome and some phenotypical properties of Lactobacillus fermentum CECT 5716, a probiotic strain isolated from human milk
Nivia Cárdenas,Jonathan Emiliano Laiño,Susana Delgado,Esther Jiménez,Marianela Juárez del Valle,Graciela Savoy de Giori,Fernando Sesma,Baltasar Mayo,Leónides Fernández,Jean Guy LeBlanc,Juan M. Rodríguez +10 more
TL;DR: Lactobacillus fermentum CECT 5716, isolated from human milk, has immunomodulatory, anti-inflammatory, and anti-infectious properties, as revealed by several in vitro and in vivo assays, which suggests a strong potential as a probiotic strain.
Journal ArticleDOI
Network analysis suggests a potentially `evil' alliance of opportunistic pathogens inhibited by a cooperative network in human milk bacterial communities
TL;DR: The ‘confrontation' between the ‘evil' alliance and ‘benign’ alliance and the shifting balance between them may be responsible for dysbiosis of the milk microbiome that permits mastitis.
Journal ArticleDOI
Microbial Community Dynamics in Mother's Milk and Infant's Mouth and Gut in Moderately Preterm Infants.
Elena Biagi,Arianna Aceti,Sara Quercia,Isadora Beghetti,Simone Rampelli,Silvia Turroni,Matteo Soverini,Angelo Vittorio Zambrini,Giacomo Faldella,Marco Candela,Luigi Corvaglia,Patrizia Brigidi +11 more
TL;DR: The findings underline the importance of encouraging not only human milk feeding, but also an early start of actual breastfeeding in preterm infants, since the infant’'s latching to the mother’s breast might constitute an independent factor helping the health-promoting assembly of the infant gut microbiome.
Journal ArticleDOI
Early-Life Gut Microbiome—The Importance of Maternal and Infant Factors in Its Establishment
TL;DR: The important role of infant feeding is reviewed, including evidence-based strategies for maternal and infant supplementation with the goal to protect and/or restore the infant gut microbiome.
Journal ArticleDOI
Respiratory Microbiome of New-Born Infants
David Gallacher,Sailesh Kotecha +1 more
TL;DR: The evidence of early airway and lung bacterial colonization and the role the microbiome has on respiratory health in the short and long term and the challenges of neonatal respiratory microbiome studies are summarized.
References
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Journal ArticleDOI
A core gut microbiome in obese and lean twins
Peter J. Turnbaugh,Micah Hamady,Tanya Yatsunenko,Brandi L. Cantarel,Alexis E. Duncan,Ruth E. Ley,Mitchell L. Sogin,William J. Jones,Bruce A. Roe,Jason P. Affourtit,Michael Egholm,Bernard Henrissat,Andrew C. Heath,Rob Knight,Jeffrey I. Gordon +14 more
TL;DR: The faecal microbial communities of adult female monozygotic and dizygotic twin pairs concordant for leanness or obesity, and their mothers are characterized to address how host genotype, environmental exposure and host adiposity influence the gut microbiome.
Journal ArticleDOI
Breastfeeding and the Use of Human Milk
TL;DR: Pediatricians play a critical role in their practices and communities as advocates of breastfeeding and thus should be knowledgeable about the health risks of not breastfeeding, the economic benefits to society of breastfeeding, and the techniques for managing and supporting the breastfeeding dyad.
Journal ArticleDOI
Gut Microbiota in Health and Disease
TL;DR: The advances in modeling and analysis of gut microbiota will further the authors' knowledge of their role in health and disease, allowing customization of existing and future therapeutic and prophylactic modalities.
Journal ArticleDOI
Vaginal microbiome of reproductive-age women
Jacques Ravel,Pawel Gajer,Zaid Abdo,G. Maria Schneider,Sara S. K. Koenig,Stacey L. McCulle,Shara Karlebach,Reshma Gorle,Jennifer Russell,Carol O. Tacket,Rebecca M. Brotman,Catherine C. Davis,Kevin A. Ault,Ligia Peralta,Larry J. Forney +14 more
TL;DR: The inherent differences within and between women in different ethnic groups strongly argues for a more refined definition of the kinds of bacterial communities normally found in healthy women and the need to appreciate differences between individuals so they can be taken into account in risk assessment and disease diagnosis.
Journal ArticleDOI
Bacterial Community Variation in Human Body Habitats Across Space and Time
Elizabeth K. Costello,Christian L. Lauber,Micah Hamady,Noah Fierer,Noah Fierer,Jeffrey I. Gordon,Rob Knight,Rob Knight +7 more
TL;DR: The results indicate that the microbiota, although personalized, varies systematically across body habitats and time; such trends may ultimately reveal how microbiome changes cause or prevent disease.