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Journal ArticleDOI

Human milk: a source of more life than we imagine

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TLDR
A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and lactation.
Abstract
The presence of bacteria in human milk has been acknowledged since the seventies. For a long time, microbiological analysis of human milk was only performed in case of infections and therefore the presence of non-pathogenic bacteria was yet unknown. During the last decades, the use of more sophisticated culture-dependent and -independent techniques, and the steady development of the -omic approaches are opening up the new concept of the ‘milk microbiome’, a complex ecosystem with a greater diversity than previously anticipated. In this review, possible mechanisms by which bacteria can reach the mammary gland (contamination versus active migration) are discussed. In addition, the potential roles of human milk for both infant and maternal health are summarised. A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and ...

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Citations
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Rôle du microbiote intestinal sur le risque palustre et mise en perspective de thérapies antipaludiques innovantes

TL;DR: In this article, the authors present an etude des interactions de microbiotes intestinaux de mammiferes (humains et souris) avec les plasmodiums montrent un effet protecteur de certaines bacteries intestinales.
DissertationDOI

Characterizing Immune-modulatory Components of Human Milk: The Fate and Function of Soluble CD14 and the Human Milk Metagenome

Tonya L. Ward
TL;DR: This paper presents a meta-analyses of the immune response to ingested soluble CD14 in animals, fostering and LPS injection and its implications for future generations of scientists and clinicians.
Journal ArticleDOI

Microbial quantitation of colostrum from healthy breastfeeding women and milk from mastitis patients.

TL;DR: Results of this study reveal a large amount of microbiota in the colostrum, and mammary microbial dysbiosis may be involved in the pathogenesis of lactational mastitis.
Book ChapterDOI

Microbiome and the Effect on Immune Response

TL;DR: Combined prenatal and postnatal supplementation seems to be crucial for the preventive effect of probiotics on infant eczema and the appropriate timing of interventions and the complex interactions between the infant immune system and the microbiome are required to identify preventive strategies to combat the asthma and allergy epidemic.
References
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Journal ArticleDOI

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Journal ArticleDOI

Breastfeeding and the Use of Human Milk

TL;DR: Pediatricians play a critical role in their practices and communities as advocates of breastfeeding and thus should be knowledgeable about the health risks of not breastfeeding, the economic benefits to society of breastfeeding, and the techniques for managing and supporting the breastfeeding dyad.
Journal ArticleDOI

Gut Microbiota in Health and Disease

TL;DR: The advances in modeling and analysis of gut microbiota will further the authors' knowledge of their role in health and disease, allowing customization of existing and future therapeutic and prophylactic modalities.
Journal ArticleDOI

Vaginal microbiome of reproductive-age women

TL;DR: The inherent differences within and between women in different ethnic groups strongly argues for a more refined definition of the kinds of bacterial communities normally found in healthy women and the need to appreciate differences between individuals so they can be taken into account in risk assessment and disease diagnosis.
Journal ArticleDOI

Bacterial Community Variation in Human Body Habitats Across Space and Time

TL;DR: The results indicate that the microbiota, although personalized, varies systematically across body habitats and time; such trends may ultimately reveal how microbiome changes cause or prevent disease.
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