Journal ArticleDOI
Human milk: a source of more life than we imagine
Prescilla V. Jeurink,J. van Bergenhenegouwen,E. Jiménez,Léon M.J. Knippels,Leónides Fernández,Johan Garssen,Jan Knol,Juan M. Rodríguez,Rosario Martín +8 more
Reads0
Chats0
TLDR
A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and lactation.Abstract:
The presence of bacteria in human milk has been acknowledged since the seventies. For a long time, microbiological analysis of human milk was only performed in case of infections and therefore the presence of non-pathogenic bacteria was yet unknown. During the last decades, the use of more sophisticated culture-dependent and -independent techniques, and the steady development of the -omic approaches are opening up the new concept of the ‘milk microbiome’, a complex ecosystem with a greater diversity than previously anticipated. In this review, possible mechanisms by which bacteria can reach the mammary gland (contamination versus active migration) are discussed. In addition, the potential roles of human milk for both infant and maternal health are summarised. A better understanding of the link between the milk microbiome and health benefit, the potential factors influencing this relationship and whether or not it can be influenced by nutrition is required to open new avenues in the field of pregnancy and ...read more
Citations
More filters
Journal ArticleDOI
Colostrum of healthy Slovenian mothers: microbiota composition and bacteriocin gene prevalence.
Tanja Obermajer,Luka Lipoglavšek,Gorazd Tompa,Primož Treven,Petra Mohar Lorbeg,Bojana Bogovič Matijašić,Irena Rogelj +6 more
TL;DR: This work provides knowledge on the colostrum microbial community composition of healthy lactating Slovenian mothers and reports bacteriocin gene prevalence.
Journal ArticleDOI
Early Factors Leading to Later Obesity: Interactions of the Microbiome, Epigenome, and Nutrition
Lilly L Chang,Josef Neu +1 more
TL;DR: The relationship of the microbial ecology of the gastrointestinal tract during early development and the consequent effects on metabolism, epigenetics, and inflammatory responses that can subsequently result in metabolic syndrome are highlighted.
Journal ArticleDOI
Early colonization of the gut microbiome and its relationship with obesity
Jena L. Dreyer,Andrea L. Liebl +1 more
TL;DR: The colonization of an infant’s gut with optimal bacteria may help reduce the risk of obesity later in life, as well as other mitigation strategies.
Journal ArticleDOI
Evaluation of Human Milk Microbiota by 16S rRNA Gene Next-Generation Sequencing (NGS) and Cultivation/MALDI-TOF Mass Spectrometry Identification.
Primož Treven,Aleksander Mahnic,Maja Rupnik,Majda Golob,Tina Pirš,Bojana Bogovič Matijašić,Petra Mohar Lorbeg +6 more
TL;DR: This study suggests that administration of probiotics to the suckling infant might influence HMM by increased abundance of lactobacilli and the presence of viable probiotic bacteria in human milk, but since this study was observational with relatively small sample size, more targeted studies are needed.
Journal ArticleDOI
Whole-Genome Comparison Uncovers Genomic Mutations between Group B Streptococci Sampled from Infected Newborns and Their Mothers
Alexandre Almeida,Adrien Villain,Caroline Joubrel,Gérald Touak,Elisabeth Sauvage,Isabelle Rosinski-Chupin,Claire Poyart,Philippe Glaser,Philippe Glaser +8 more
TL;DR: The work showed that GBS strains in carriage and disease scenarios might undergo adaptive changes following colonization, and suggested that during GBS's progression to disease, particular variants are positively selected, contributing to the ability of this bacterium to infect its host.
References
More filters
Journal ArticleDOI
A core gut microbiome in obese and lean twins
Peter J. Turnbaugh,Micah Hamady,Tanya Yatsunenko,Brandi L. Cantarel,Alexis E. Duncan,Ruth E. Ley,Mitchell L. Sogin,William J. Jones,Bruce A. Roe,Jason P. Affourtit,Michael Egholm,Bernard Henrissat,Andrew C. Heath,Rob Knight,Jeffrey I. Gordon +14 more
TL;DR: The faecal microbial communities of adult female monozygotic and dizygotic twin pairs concordant for leanness or obesity, and their mothers are characterized to address how host genotype, environmental exposure and host adiposity influence the gut microbiome.
Journal ArticleDOI
Breastfeeding and the Use of Human Milk
TL;DR: Pediatricians play a critical role in their practices and communities as advocates of breastfeeding and thus should be knowledgeable about the health risks of not breastfeeding, the economic benefits to society of breastfeeding, and the techniques for managing and supporting the breastfeeding dyad.
Journal ArticleDOI
Gut Microbiota in Health and Disease
TL;DR: The advances in modeling and analysis of gut microbiota will further the authors' knowledge of their role in health and disease, allowing customization of existing and future therapeutic and prophylactic modalities.
Journal ArticleDOI
Vaginal microbiome of reproductive-age women
Jacques Ravel,Pawel Gajer,Zaid Abdo,G. Maria Schneider,Sara S. K. Koenig,Stacey L. McCulle,Shara Karlebach,Reshma Gorle,Jennifer Russell,Carol O. Tacket,Rebecca M. Brotman,Catherine C. Davis,Kevin A. Ault,Ligia Peralta,Larry J. Forney +14 more
TL;DR: The inherent differences within and between women in different ethnic groups strongly argues for a more refined definition of the kinds of bacterial communities normally found in healthy women and the need to appreciate differences between individuals so they can be taken into account in risk assessment and disease diagnosis.
Journal ArticleDOI
Bacterial Community Variation in Human Body Habitats Across Space and Time
Elizabeth K. Costello,Christian L. Lauber,Micah Hamady,Noah Fierer,Noah Fierer,Jeffrey I. Gordon,Rob Knight,Rob Knight +7 more
TL;DR: The results indicate that the microbiota, although personalized, varies systematically across body habitats and time; such trends may ultimately reveal how microbiome changes cause or prevent disease.