Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
TLDR
In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
Citations
More filters
Journal Article
A possible central mechanism in autism spectrum disorders, part 1.
TL;DR: It has now been shown that chronic microglial activation is present in autistic brains from age 5 years to age 44 years, and the term immunoexcitotoxicity is coined, which is described in this article.
Journal ArticleDOI
The use and misuse of biomedical data: is bigger really better?
Sharona Hoffman,Andy Podgurski +1 more
TL;DR: Very large biomedical research databases, containing electronic health records (EHR) and genomic data from millions of patients, have been heralded recently for their potential to accelerate scient... as mentioned in this paper.
Journal ArticleDOI
OUP accepted manuscript
TL;DR: In this article , the history and dangers of health misinformation and disinformation in social media are discussed, as well as tools for identifying and responding to misinformation and proposing other ethical considerations for social media.
Journal ArticleDOI
A crisis of governance
TL;DR: There is a need for a rebalancing of power in the United Kingdom, both among the three branches of government and its constituent parts (England, Scotland, Wales, and Northern Ireland), and for now much can be done to hold the executive to account and to be aware of the dangers faced by public health.
Dissertation
The Political Economy of Autism
TL;DR: It is argued that autism is not only a public health issue, it also represents a crisis of political economy and capitalism has transformed science and medicine from a focus on use values to afocus on exchange values, and regulation is largely a reflection of political power not scientific evidence.
References
More filters
Journal ArticleDOI
Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
Journal ArticleDOI
Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
Journal ArticleDOI
A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.