Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
TLDR
In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
Citations
More filters
Journal ArticleDOI
Prevalence of Childhood Disintegrative Disorder
TL;DR: The conclusion is that CDD is very rare and its prevalence is 60 times less than that for autistic disorder, assuming a prevalence of 10 per 10,000 for autism.
Journal ArticleDOI
Progressive reduction in treatment-related deaths in Medical Research Council childhood lymphoblastic leukaemia trials from 1980 to 1997 (UKALL VIII, X and XI).
Darren Hargrave,Ian Hann,Susan M. Richards,Frank Hill,John S. Lilleyman,Sally E. Kinsey,C. C. Bailey,Jm M. Chessells,Chris Mitchell,Osborn B. Eden +9 more
TL;DR: While improved supportive care has reduced the incidence of TRD, there is still scope for further reduction by prompt treatment of suspected infection, and maintenance of herd immunity remains of vital importance in avoiding deaths from measles.
Journal ArticleDOI
Brief report: immune factors in autism: a critical review.
TL;DR: Intensive well-controlled epidemiological and bench studies need to be carried out in defined and carefully controlled study subjects to establish the cellular and molecular basis of autism.
Journal ArticleDOI
Social movements, knowledge and public policy: the case of autism activism in Canada and the US
Michael Orsini,Miriam Smith +1 more
TL;DR: The role of social movements in the policy process and the ways in which movements interact with, access, and deploy expert knowledge is explored in this paper, where the authors argue that citizens are more than the undifferentiated lump that appears in the technocratic model under the guise of citizen engagement.
Journal ArticleDOI
Parental beliefs about cause and course of their child's autism and outcomes of their beliefs: a review of the literature.
TL;DR: It was found that parents hold a wide variety of beliefs about the cause of their child's autism, including genetic factors, events surrounding the child's birth, and environmental influences in the early childhood period.
References
More filters
Journal ArticleDOI
Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
Journal ArticleDOI
Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
Journal ArticleDOI
A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.