Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
TLDR
In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
Citations
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Regression in autistic spectrum disorders.
TL;DR: It is argued that regressive autistic spectrum disorders can be conceptualized on a spectrum with other regressive disorders that may share common pathophysiological features.
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Gluten-free and casein-free diets in the treatment of autism spectrum disorders: a systematic review
TL;DR: Critical analysis of each study's methodological rigor and results reveal that the current corpus of research does not support the use of GFCF diets in the treatment of ASD.
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Genetic and immunologic considerations in autism.
TL;DR: This review summarizes advances in the molecular genetics of autism, as well as recently emerging concerns addressing the disease incidence and triggering factors, and discusses evidence of similar phenomena in autism.
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A Gluten-Free Diet as an Intervention for Autism and Associated Spectrum Disorders: Preliminary Findings
TL;DR: Results suggested that participants on a gluten-free diet showed an improvement on a number of behavioural measures, however there was no significant decrease in specific urinary compounds excreted when compared with controls and a gluten challenge group.
Journal ArticleDOI
Vaccine risks: real, perceived and unknown.
TL;DR: Modernization of the vaccine safety infrastructure commensurate with the current investment in vaccine development will be needed if the full promise of new vaccines made possible by the biotechnology revolution are likely to be fulfilled.
References
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Journal ArticleDOI
Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
Journal ArticleDOI
Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
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A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.