Journal ArticleDOI
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
Andrew J. Wakefield,S. H. Murch,A Anthony,J Linnell,D M Casson,M Malik,M Berelowitz,Ap Dhillon,Mike Thomson,Peter Harvey,A Valentine,S Davies,J A Walker-Smith +12 more
TLDR
In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.About:
This article is published in The Lancet.The article was published on 1998-02-28. It has received 2505 citations till now. The article focuses on the topics: Pervasive developmental disorder & Lymphoid hyperplasia.read more
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Response to "Theoretical aspects of autism: causes--a review" by Ratajczak, HV (Journal of Immunotoxicology 8:68-79, 2011).
TL;DR: Several recent studies indicate that vaccination, specifically the vaccination against measles-mumps-rubella (MMR), does not increase the risk of autism, and the vaccine controversy arose from a single paper published in 1998, suggesting that the MMR vaccine was linked to autism.
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Autoimmune and gastrointestinal dysfunctions: does a subset of children with autism reveal a broader connection?
Amy C. Brown,Lewis Mehl-Madrona +1 more
TL;DR: Sufficient evidence exists to support that a subgroup of children with autism may suffer from concomitant immune-related GI symptoms, and the available literature on the immunological and GI aspects of autism is evaluated.
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Similar challenges but different responses: Media coverage of measles vaccination in the UK and China:
TL;DR: A content analysis of newspaper coverage of vaccination issues in the UK and China shows that the government-supported ‘mainstream position’ dominates the Chinese coverage while the British media frequently refer to criticism and controversy.
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MMR Catch up Campaign: reasons for refusal to consent
I Hadjikoumi,K V Niekerk,C Scott +2 more
TL;DR: A descriptive study looking at parents’ reasons for refusing MMR vaccination, analysing retrospectively all returned consent forms, from 50 primary schools from the Royal Borough of Kingston between December 2004 and April 2005.
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Do terbutaline- and mold-associated impairments of the brain and lung relate to autism?
TL;DR: Neuropsychological abnormalities were more frequent in mold-exp exposed than in terbutaline-exposed children and included digit symbol substitution, peg placement, fingertip number writing errors, and picture completion and the most frequent abnormality in both groups was balance.
References
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Alpha-1-antitrypsin, autism, and cœliac disease
Book
The Autistic Spectrum
TL;DR: A simple system of subgrouping based solely on a description of the type of social impairment will be used, which avoids the confusion inherent in trying to identify the named syndromes.
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Abnormal intestinal permeability in children with autism.
Patrizia D'Eufemia,Mauro Celli,R. Finocchiaro,Lucia Pacifico,L Viozzi,M. Zaccagnini,Ettore Cardi,Omero Giardini +7 more
TL;DR: It is speculated that an altered intestinal permeability could represent a possible mechanism for the increased passage through the gut mucosa of peptides derived from foods with subsequent behavioural abnormalities.
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A neurochemical theory of autism
TL;DR: Panksepp et al. as discussed by the authors put forward the idea that autism is an emotional disturbance arising from an upset in the opiate systems in the brain, and hence proposed, as a possibility, opiate antagonist therapy for the autistic syndrome.